Bell EL - Search Results

1

Targeting the mitochondria for cancer therapy: regulation of hypoxia-inducible factor by mitochondria.

Bell EL, Klimova T, Chandel NS. Bell EL, et al. Antioxid Redox Signal. 2008 Mar;10(3):635-40. doi: 10.1089/ars.2007.1655. Antioxid Redox Signal. 2008. PMID: 17999628

2

Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis.

Guzy RD, Sharma B, Bell E, Chandel NS, Schumacker PT. Guzy RD, et al. Mol Cell Biol. 2008 Jan;28(2):718-31. doi: 10.1128/MCB.01338-07. Epub 2007 Oct 29. Mol Cell Biol. 2008. PMID: 17967865 Free PMC article.

3

Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation.

Brunelle JK, Bell EL, Quesada NM, Vercauteren K, Tiranti V, Zeviani M, Scarpulla RC, Chandel NS. Brunelle JK, et al. Among authors: bell el. Cell Metab. 2005 Jun;1(6):409-14. doi: 10.1016/j.cmet.2005.05.002. Cell Metab. 2005. PMID: 16054090 Free article.

4

Mitochondrial regulation of oxygen sensing.

Bell EL, Emerling BM, Chandel NS. Bell EL, et al. Mitochondrion. 2005 Oct;5(5):322-32. doi: 10.1016/j.mito.2005.06.005. Mitochondrion. 2005. PMID: 16146708 Review.

5

The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production.

Bell EL, Klimova TA, Eisenbart J, Moraes CT, Murphy MP, Budinger GR, Chandel NS. Bell EL, et al. J Cell Biol. 2007 Jun 18;177(6):1029-36. doi: 10.1083/jcb.200609074. Epub 2007 Jun 11. J Cell Biol. 2007. PMID: 17562787 Free PMC article.

6

Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia.

Bell EL, Klimova TA, Eisenbart J, Schumacker PT, Chandel NS. Bell EL, et al. Mol Cell Biol. 2007 Aug;27(16):5737-45. doi: 10.1128/MCB.02265-06. Epub 2007 Jun 11. Mol Cell Biol. 2007. PMID: 17562866 Free PMC article.

7

Mitochondrial oxygen sensing: regulation of hypoxia-inducible factor by mitochondrial generated reactive oxygen species.

Bell EL, Chandel NS. Bell EL, et al. Essays Biochem. 2007;43:17-27. doi: 10.1042/BSE0430017. Essays Biochem. 2007. PMID: 17705790 Review.

8

Genetics of mitochondrial electron transport chain in regulating oxygen sensing.

Bell EL, Chandel NS. Bell EL, et al. Methods Enzymol. 2007;435:447-61. doi: 10.1016/S0076-6879(07)35023-4. Methods Enzymol. 2007. PMID: 17998068

9

Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS.

Klimova TA, Bell EL, Shroff EH, Weinberg FD, Snyder CM, Dimri GP, Schumacker PT, Budinger GR, Chandel NS. Klimova TA, et al. Among authors: bell el. FASEB J. 2009 Mar;23(3):783-94. doi: 10.1096/fj.08-114256. Epub 2008 Oct 23. FASEB J. 2009. PMID: 18948382 Free PMC article.

10

Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution.

Soberanes S, Urich D, Baker CM, Burgess Z, Chiarella SE, Bell EL, Ghio AJ, De Vizcaya-Ruiz A, Liu J, Ridge KM, Kamp DW, Chandel NS, Schumacker PT, Mutlu GM, Budinger GR. Soberanes S, et al. Among authors: bell el. J Biol Chem. 2009 Jan 23;284(4):2176-86. doi: 10.1074/jbc.M808844200. Epub 2008 Nov 25. J Biol Chem. 2009. PMID: 19033436 Free PMC article.

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