DeBerardinis RJ - Search Results

1

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.

DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB. DeBerardinis RJ, et al. Cell Metab. 2008 Jan;7(1):11-20. doi: 10.1016/j.cmet.2007.10.002. Cell Metab. 2008. PMID: 18177721 Free article. Review.

2

The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation.

Buzzai M, Bauer DE, Jones RG, Deberardinis RJ, Hatzivassiliou G, Elstrom RL, Thompson CB. Buzzai M, et al. Among authors: deberardinis rj. Oncogene. 2005 Jun 16;24(26):4165-73. doi: 10.1038/sj.onc.1208622. Oncogene. 2005. PMID: 15806154

3

Autophagy in metazoans: cell survival in the land of plenty.

Lum JJ, DeBerardinis RJ, Thompson CB. Lum JJ, et al. Among authors: deberardinis rj. Nat Rev Mol Cell Biol. 2005 Jun;6(6):439-48. doi: 10.1038/nrm1660. Nat Rev Mol Cell Biol. 2005. PMID: 15928708 Review.

4

Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth.

Deberardinis RJ, Lum JJ, Thompson CB. Deberardinis RJ, et al. J Biol Chem. 2006 Dec 8;281(49):37372-80. doi: 10.1074/jbc.M608372200. Epub 2006 Oct 9. J Biol Chem. 2006. PMID: 17030509 Free article.

5

The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis.

Lum JJ, Bui T, Gruber M, Gordan JD, DeBerardinis RJ, Covello KL, Simon MC, Thompson CB. Lum JJ, et al. Among authors: deberardinis rj. Genes Dev. 2007 May 1;21(9):1037-49. doi: 10.1101/gad.1529107. Epub 2007 Apr 16. Genes Dev. 2007. PMID: 17437992 Free PMC article.

6

Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth.

Buzzai M, Jones RG, Amaravadi RK, Lum JJ, DeBerardinis RJ, Zhao F, Viollet B, Thompson CB. Buzzai M, et al. Among authors: deberardinis rj. Cancer Res. 2007 Jul 15;67(14):6745-52. doi: 10.1158/0008-5472.CAN-06-4447. Cancer Res. 2007. PMID: 17638885 Free article.

7

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.

DeBerardinis RJ, Mancuso A, Daikhin E, Nissim I, Yudkoff M, Wehrli S, Thompson CB. DeBerardinis RJ, et al. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19345-50. doi: 10.1073/pnas.0709747104. Epub 2007 Nov 21. Proc Natl Acad Sci U S A. 2007. PMID: 18032601 Free PMC article.

8

Brick by brick: metabolism and tumor cell growth.

Deberardinis RJ, Sayed N, Ditsworth D, Thompson CB. Deberardinis RJ, et al. Curr Opin Genet Dev. 2008 Feb;18(1):54-61. doi: 10.1016/j.gde.2008.02.003. Epub 2008 Apr 2. Curr Opin Genet Dev. 2008. PMID: 18387799 Free PMC article. Review.

9

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.

Wise DR, DeBerardinis RJ, Mancuso A, Sayed N, Zhang XY, Pfeiffer HK, Nissim I, Daikhin E, Yudkoff M, McMahon SB, Thompson CB. Wise DR, et al. Among authors: deberardinis rj. Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18782-7. doi: 10.1073/pnas.0810199105. Epub 2008 Nov 24. Proc Natl Acad Sci U S A. 2008. PMID: 19033189 Free PMC article.

10

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation.

Krawczyk CM, Holowka T, Sun J, Blagih J, Amiel E, DeBerardinis RJ, Cross JR, Jung E, Thompson CB, Jones RG, Pearce EJ. Krawczyk CM, et al. Among authors: deberardinis rj. Blood. 2010 Jun 10;115(23):4742-9. doi: 10.1182/blood-2009-10-249540. Epub 2010 Mar 29. Blood. 2010. PMID: 20351312 Free PMC article.

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