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2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists.
Shireman BT, Dvorak CA, Rudolph DA, Bonaventure P, Nepomuceno D, Dvorak L, Miller KL, Lovenberg TW, Carruthers NI. Shireman BT, et al. Among authors: lovenberg tw. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2103-8. doi: 10.1016/j.bmcl.2008.01.090. Epub 2008 Jan 30. Bioorg Med Chem Lett. 2008. PMID: 18282705
Novel human histamine H(3) receptor antagonists.
Shah C, McAtee L, Breitenbucher JG, Rudolph D, Li X, Lovenberg TW, Mazur C, Wilson SJ, Carruthers NI. Shah C, et al. Among authors: lovenberg tw. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3309-12. doi: 10.1016/s0960-894x(02)00738-2. Bioorg Med Chem Lett. 2002. PMID: 12392739
Non-imidazole heterocyclic histamine H3 receptor antagonists.
Chai W, Breitenbucher JG, Kwok A, Li X, Wong V, Carruthers NI, Lovenberg TW, Mazur C, Wilson SJ, Axe FU, Jones TK. Chai W, et al. Among authors: lovenberg tw. Bioorg Med Chem Lett. 2003 May 19;13(10):1767-70. doi: 10.1016/s0960-894x(03)00299-3. Bioorg Med Chem Lett. 2003. PMID: 12729661
The first potent and selective non-imidazole human histamine H4 receptor antagonists.
Jablonowski JA, Grice CA, Chai W, Dvorak CA, Venable JD, Kwok AK, Ly KS, Wei J, Baker SM, Desai PJ, Jiang W, Wilson SJ, Thurmond RL, Karlsson L, Edwards JP, Lovenberg TW, Carruthers NI. Jablonowski JA, et al. Among authors: lovenberg tw. J Med Chem. 2003 Sep 11;46(19):3957-60. doi: 10.1021/jm0341047. J Med Chem. 2003. PMID: 12954048
Novel non-peptidic neuropeptide Y Y2 receptor antagonists.
Jablonowski JA, Chai W, Li X, Rudolph DA, Murray WV, Youngman MA, Dax SL, Nepomuceno D, Bonaventure P, Lovenberg TW, Carruthers NI. Jablonowski JA, et al. Among authors: lovenberg tw. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1239-42. doi: 10.1016/j.bmcl.2003.12.057. Bioorg Med Chem Lett. 2004. PMID: 14980673
Aplysamine-1 and related analogs as histamine H3 receptor antagonists.
Swanson DM, Wilson SJ, Boggs JD, Xiao W, Apodaca R, Barbier AJ, Lovenberg TW, Carruthers NI. Swanson DM, et al. Among authors: lovenberg tw. Bioorg Med Chem Lett. 2006 Feb 15;16(4):897-900. doi: 10.1016/j.bmcl.2005.11.003. Epub 2005 Nov 21. Bioorg Med Chem Lett. 2006. PMID: 16300945
171 results