Fernández-Salas E - Search Results

1

Novel chimeras of botulinum neurotoxins A and E unveil contributions from the binding, translocation, and protease domains to their functional characteristics.

Wang J, Meng J, Lawrence GW, Zurawski TH, Sasse A, Bodeker MO, Gilmore MA, Fernández-Salas E, Francis J, Steward LE, Aoki KR, Dolly JO. Wang J, et al. J Biol Chem. 2008 Jun 20;283(25):16993-7002. doi: 10.1074/jbc.M710442200. Epub 2008 Apr 8. J Biol Chem. 2008. PMID: 18400760 Free article.

2

Plasma membrane localization signals in the light chain of botulinum neurotoxin.

Fernández-Salas E, Steward LE, Ho H, Garay PE, Sun SW, Gilmore MA, Ordas JV, Wang J, Francis J, Aoki KR. Fernández-Salas E, et al. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3208-13. doi: 10.1073/pnas.0400229101. Epub 2004 Feb 24. Proc Natl Acad Sci U S A. 2004. PMID: 14982988 Free PMC article.

3

Is the light chain subcellular localization an important factor in botulinum toxin duration of action?

Fernández-Salas E, Ho H, Garay P, Steward LE, Aoki KR. Fernández-Salas E, et al. Mov Disord. 2004 Mar;19 Suppl 8:S23-34. doi: 10.1002/mds.20006. Mov Disord. 2004. PMID: 15027051

4

Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A).

Jacky BP, Garay PE, Dupuy J, Nelson JB, Cai B, Molina Y, Wang J, Steward LE, Broide RS, Francis J, Aoki KR, Stevens RC, Fernández-Salas E. Jacky BP, et al. PLoS Pathog. 2013;9(5):e1003369. doi: 10.1371/journal.ppat.1003369. Epub 2013 May 16. PLoS Pathog. 2013. PMID: 23696738 Free PMC article.

5

A Highly Specific Monoclonal Antibody for Botulinum Neurotoxin Type A-Cleaved SNAP25.

Rhéaume C, Cai BB, Wang J, Fernández-Salas E, Aoki KR, Francis J, Broide RS. Rhéaume C, et al. Toxins (Basel). 2015 Jun 24;7(7):2354-70. doi: 10.3390/toxins7072354. Toxins (Basel). 2015. PMID: 26114335 Free PMC article.

6

Botulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassay.

Fernández-Salas E, Wang J, Molina Y, Nelson JB, Jacky BP, Aoki KR. Fernández-Salas E, et al. PLoS One. 2012;7(11):e49516. doi: 10.1371/journal.pone.0049516. Epub 2012 Nov 21. PLoS One. 2012. PMID: 23185348 Free PMC article.

7

p53 and tumor necrosis factor alpha regulate the expression of a mitochondrial chloride channel protein.

Fernández-Salas E, Sagar M, Cheng C, Yuspa SH, Weinberg WC. Fernández-Salas E, et al. J Biol Chem. 1999 Dec 17;274(51):36488-97. doi: 10.1074/jbc.274.51.36488. J Biol Chem. 1999. PMID: 10593946 Free article.

8

The organellular chloride channel protein CLIC4/mtCLIC translocates to the nucleus in response to cellular stress and accelerates apoptosis.

Suh KS, Mutoh M, Nagashima K, Fernandez-Salas E, Edwards LE, Hayes DD, Crutchley JM, Marin KG, Dumont RA, Levy JM, Cheng C, Garfield S, Yuspa SH. Suh KS, et al. J Biol Chem. 2004 Feb 6;279(6):4632-41. doi: 10.1074/jbc.M311632200. Epub 2003 Nov 10. J Biol Chem. 2004. PMID: 14610078 Free article.

9

Septin dynamics are essential for exocytosis.

Tokhtaeva E, Capri J, Marcus EA, Whitelegge JP, Khuzakhmetova V, Bukharaeva E, Deiss-Yehiely N, Dada LA, Sachs G, Fernandez-Salas E, Vagin O. Tokhtaeva E, et al. J Biol Chem. 2015 Feb 27;290(9):5280-97. doi: 10.1074/jbc.M114.616201. Epub 2015 Jan 9. J Biol Chem. 2015. PMID: 25575596 Free PMC article.

10

Recruitment of septin cytoskeletal proteins by botulinum toxin A protease determines its remarkable stability.

Vagin O, Tokhtaeva E, Garay PE, Souda P, Bassilian S, Whitelegge JP, Lewis R, Sachs G, Wheeler L, Aoki R, Fernandez-Salas E. Vagin O, et al. J Cell Sci. 2014 Aug 1;127(Pt 15):3294-308. doi: 10.1242/jcs.146324. Epub 2014 Jun 13. J Cell Sci. 2014. PMID: 24928902 Free PMC article.

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