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Tuberculosis antigen-induced expression of IFN-α in tuberculosis patients inhibits production of IL-1β.
Ma J, Yang B, Yu S, Zhang Y, Zhang X, Lao S, Chen X, Li B, Wu C. Ma J, et al. Among authors: yang b. FASEB J. 2014 Jul;28(7):3238-48. doi: 10.1096/fj.13-247056. Epub 2014 Mar 27. FASEB J. 2014. PMID: 24675363
Our findings demonstrate that IFN-alpha employs distinct pathways for regulating IL-1beta production and reveal that in the case of M.tb infection, the induction of IFN-alpha and IFN-gamma might be associated with M.tb immune escape and disease progression in infected humans.-Ma, …
Our findings demonstrate that IFN-alpha employs distinct pathways for regulating IL-1beta production and reveal that in the case of M.tb inf …
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