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Protein disaggregation by the AAA+ chaperone ClpB involves partial threading of looped polypeptide segments.
Nat Struct Mol Biol. 2008 Jun;15(6):641-50. doi: 10.1038/nsmb.1425. Epub 2008 May 18.
Nat Struct Mol Biol. 2008.
PMID: 18488042
M domains couple the ClpB threading motor with the DnaK chaperone activity.
Haslberger T, Weibezahn J, Zahn R, Lee S, Tsai FT, Bukau B, Mogk A.
Haslberger T, et al.
Mol Cell. 2007 Jan 26;25(2):247-60. doi: 10.1016/j.molcel.2006.11.008.
Mol Cell. 2007.
PMID: 17244532
Free article.
Item in Clipboard
Towards a unifying mechanism for ClpB/Hsp104-mediated protein disaggregation and prion propagation.
Haslberger T, Bukau B, Mogk A.
Haslberger T, et al.
Biochem Cell Biol. 2010 Feb;88(1):63-75. doi: 10.1139/o09-118.
Biochem Cell Biol. 2010.
PMID: 20130680
Review.
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Common and specific mechanisms of AAA+ proteins involved in protein quality control.
Mogk A, Haslberger T, Tessarz P, Bukau B.
Mogk A, et al. Among authors: haslberger t.
Biochem Soc Trans. 2008 Feb;36(Pt 1):120-5. doi: 10.1042/BST0360120.
Biochem Soc Trans. 2008.
PMID: 18208398
Review.
Item in Clipboard
Assessing the Impact of Immunogenicity and Improving Prediction of Trough Concentrations: Population Pharmacokinetic Modeling of Adalimumab in Patients with Crohn's Disease and Ulcerative Colitis.
Ponce-Bobadilla AV, Stodtmann S, Chen MJ, Winzenborg I, Mensing S, Blaes J, Haslberger T, Laplanche L, Dreher I, Mostafa NM.
Ponce-Bobadilla AV, et al. Among authors: haslberger t.
Clin Pharmacokinet. 2023 Apr;62(4):623-634. doi: 10.1007/s40262-023-01221-x. Epub 2023 Mar 11.
Clin Pharmacokinet. 2023.
PMID: 36905528
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Recommendations for singlet-based approach in ligand binding assays: an IQ Consortium perspective.
Pillutla R, Gorovits B, Gleason C, Quiroz J, Christopher D, Braun M, Brockus C, Donaldson D, Haslberger T, He L, Qian M, Sydor J, Wickremsinhe E, Williams L.
Pillutla R, et al. Among authors: haslberger t.
Bioanalysis. 2020 Jun;12(12):823-834. doi: 10.4155/bio-2020-0094. Epub 2020 Jun 19.
Bioanalysis. 2020.
PMID: 32558588
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European Bioanalysis Forum feedback on draft ICH M10 guideline on bioanalytical method validation during the Step 2b public consultation period.
Timmerman P, Goodman J, Golob M, Haslberger T, Knutsson M, Nelson R, Verhaeghe T, White S.
Timmerman P, et al. Among authors: haslberger t.
Bioanalysis. 2020 Mar;12(6s):1-11. doi: 10.4155/bio-2020-0065. Epub 2020 Apr 23.
Bioanalysis. 2020.
PMID: 32323555
Free article.
Item in Clipboard
Depletion efficiency and recovery of trace markers from a multiparameter immunodepletion column.
Brand J, Haslberger T, Zolg W, Pestlin G, Palme S.
Brand J, et al. Among authors: haslberger t.
Proteomics. 2006 Jun;6(11):3236-42. doi: 10.1002/pmic.200500864.
Proteomics. 2006.
PMID: 16645986
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