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Therapeutic administration of KM+ lectin protects mice against Paracoccidioides brasiliensis infection via interleukin-12 production in a toll-like receptor 2-dependent mechanism.
Coltri KC, Oliveira LL, Pinzan CF, Vendruscolo PE, Martinez R, Goldman MH, Panunto-Castelo A, Roque-Barreira MC. Coltri KC, et al. Among authors: martinez r. Am J Pathol. 2008 Aug;173(2):423-32. doi: 10.2353/ajpath.2008.080126. Epub 2008 Jul 3. Am J Pathol. 2008. PMID: 18599609 Free PMC article.
Paracoccin, a GlcNAc-binding lectin from Paracoccidioides brasiliensis, binds to laminin and induces TNF-alpha production by macrophages.
Coltri KC, Casabona-Fortunato AS, Gennari-Cardoso ML, Pinzan CF, Ruas LP, Mariano VS, Martinez R, Rosa JC, Panunto-Castelo A, Roque-Barreira MC. Coltri KC, et al. Among authors: martinez r. Microbes Infect. 2006 Mar;8(3):704-13. doi: 10.1016/j.micinf.2005.09.008. Epub 2006 Jan 17. Microbes Infect. 2006. PMID: 16476564 Free article.
Inducible nitric oxide synthase-deficient mice show exacerbated inflammatory process and high production of both Th1 and Th2 cytokines during paracoccidioidomycosis.
Livonesi MC, Rossi MA, de Souto JT, Campanelli AP, de Sousa RL, Maffei CM, Ferreira BR, Martinez R, da Silva JS. Livonesi MC, et al. Among authors: martinez r. Microbes Infect. 2009 Jan;11(1):123-32. doi: 10.1016/j.micinf.2008.10.015. Epub 2008 Nov 24. Microbes Infect. 2009. PMID: 19063988 Free article.
3,169 results