Mandinova A - Search Results

1

EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer.

Kolev V, Mandinova A, Guinea-Viniegra J, Hu B, Lefort K, Lambertini C, Neel V, Dummer R, Wagner EF, Dotto GP. Kolev V, et al. Among authors: mandinova a. Nat Cell Biol. 2008 Aug;10(8):902-11. doi: 10.1038/ncb1750. Epub 2008 Jul 6. Nat Cell Biol. 2008. PMID: 18604200 Free PMC article.

2

The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response.

Mandinova A, Lefort K, Tommasi di Vignano A, Stonely W, Ostano P, Chiorino G, Iwaki H, Nakanishi J, Dotto GP. Mandinova A, et al. EMBO J. 2008 Apr 23;27(8):1243-54. doi: 10.1038/emboj.2008.45. Epub 2008 Apr 3. EMBO J. 2008. PMID: 18388864 Free PMC article.

3

A positive FGFR3/FOXN1 feedback loop underlies benign skin keratosis versus squamous cell carcinoma formation in humans.

Mandinova A, Kolev V, Neel V, Hu B, Stonely W, Lieb J, Wu X, Colli C, Han R, Pazin MJ, Ostano P, Dummer R, Brissette JL, Dotto GP. Mandinova A, et al. J Clin Invest. 2009 Oct;119(10):3127-37. doi: 10.1172/JCI38543. J Clin Invest. 2009. PMID: 19729838 Free PMC article.

4

Small GTPase RhoE/Rnd3 is a critical regulator of Notch1 signaling.

Zhu Z, Todorova K, Lee KK, Wang J, Kwon E, Kehayov I, Kim HG, Kolev V, Dotto GP, Lee SW, Mandinova A. Zhu Z, et al. Among authors: mandinova a. Cancer Res. 2014 Apr 1;74(7):2082-93. doi: 10.1158/0008-5472.CAN-12-0452. Epub 2014 Feb 13. Cancer Res. 2014. PMID: 24525741 Free PMC article.

5

Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation.

Nguyen BC, Lefort K, Mandinova A, Antonini D, Devgan V, Della Gatta G, Koster MI, Zhang Z, Wang J, Tommasi di Vignano A, Kitajewski J, Chiorino G, Roop DR, Missero C, Dotto GP. Nguyen BC, et al. Among authors: mandinova a. Genes Dev. 2006 Apr 15;20(8):1028-42. doi: 10.1101/gad.1406006. Genes Dev. 2006. PMID: 16618808 Free PMC article.

6

Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases.

Lefort K, Mandinova A, Ostano P, Kolev V, Calpini V, Kolfschoten I, Devgan V, Lieb J, Raffoul W, Hohl D, Neel V, Garlick J, Chiorino G, Dotto GP. Lefort K, et al. Among authors: mandinova a. Genes Dev. 2007 Mar 1;21(5):562-77. doi: 10.1101/gad.1484707. Genes Dev. 2007. PMID: 17344417 Free PMC article.

7

The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.

Kwon E, Todorova K, Wang J, Horos R, Lee KK, Neel VA, Negri GL, Sorensen PH, Lee SW, Hentze MW, Mandinova A. Kwon E, et al. Among authors: mandinova a. Nat Commun. 2018 Apr 30;9(1):1734. doi: 10.1038/s41467-018-04092-0. Nat Commun. 2018. PMID: 29712925 Free PMC article.

8

Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis.

Hiraki M, Hwang SY, Cao S, Ramadhar TR, Byun S, Yoon KW, Lee JH, Chu K, Gurkar AU, Kolev V, Zhang J, Namba T, Murphy ME, Newman DJ, Mandinova A, Clardy J, Lee SW. Hiraki M, et al. Among authors: mandinova a. Chem Biol. 2015 Sep 17;22(9):1206-16. doi: 10.1016/j.chembiol.2015.07.016. Epub 2015 Aug 27. Chem Biol. 2015. PMID: 26320861 Free PMC article.

9

Sustained Akt Activity Is Required to Maintain Cell Viability in Seborrheic Keratosis, a Benign Epithelial Tumor.

Neel VA, Todorova K, Wang J, Kwon E, Kang M, Liu Q, Gray N, Lee SW, Mandinova A. Neel VA, et al. Among authors: mandinova a. J Invest Dermatol. 2016 Mar;136(3):696-705. doi: 10.1016/j.jid.2015.12.023. Epub 2015 Dec 29. J Invest Dermatol. 2016. PMID: 26739095 Free article.

10

High-throughput, high-content screening for novel pigmentation regulators using a keratinocyte/melanocyte co-culture system.

Lee JH, Chen H, Kolev V, Aull KH, Jung I, Wang J, Miyamoto S, Hosoi J, Mandinova A, Fisher DE. Lee JH, et al. Among authors: mandinova a. Exp Dermatol. 2014 Feb;23(2):125-9. doi: 10.1111/exd.12322. Exp Dermatol. 2014. PMID: 24438532 Free PMC article.

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