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Mutations in CBL occur frequently in juvenile myelomonocytic leukemia.
Loh ML, Sakai DS, Flotho C, Kang M, Fliegauf M, Archambeault S, Mullighan CG, Chen L, Bergstraesser E, Bueso-Ramos CE, Emanuel PD, Hasle H, Issa JP, van den Heuvel-Eibrink MM, Locatelli F, Stary J, Trebo M, Wlodarski M, Zecca M, Shannon KM, Niemeyer CM. Loh ML, et al. Among authors: shannon km. Blood. 2009 Aug 27;114(9):1859-63. doi: 10.1182/blood-2009-01-198416. Epub 2009 Jul 1. Blood. 2009. PMID: 19571318 Free PMC article.
NRASG12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia.
Sachs Z, LaRue RS, Nguyen HT, Sachs K, Noble KE, Mohd Hassan NA, Diaz-Flores E, Rathe SK, Sarver AL, Bendall SC, Ha NA, Diers MD, Nolan GP, Shannon KM, Largaespada DA. Sachs Z, et al. Among authors: shannon km. Blood. 2014 Nov 20;124(22):3274-83. doi: 10.1182/blood-2013-08-521708. Epub 2014 Oct 14. Blood. 2014. PMID: 25316678 Free PMC article.
Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency.
Sachs Z, Been RA, DeCoursin KJ, Nguyen HT, Mohd Hassan NA, Noble-Orcutt KE, Eckfeldt CE, Pomeroy EJ, Diaz-Flores E, Geurts JL, Diers MD, Hasz DE, Morgan KJ, MacMillan ML, Shannon KM, Largaespada DA, Wiesner SM. Sachs Z, et al. Among authors: shannon km. Haematologica. 2016 Oct;101(10):1190-1199. doi: 10.3324/haematol.2015.136002. Epub 2016 Jul 14. Haematologica. 2016. PMID: 27418650 Free PMC article.
Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis.
Loh ML, Vattikuti S, Schubbert S, Reynolds MG, Carlson E, Lieuw KH, Cheng JW, Lee CM, Stokoe D, Bonifas JM, Curtiss NP, Gotlib J, Meshinchi S, Le Beau MM, Emanuel PD, Shannon KM. Loh ML, et al. Among authors: shannon km. Blood. 2004 Mar 15;103(6):2325-31. doi: 10.1182/blood-2003-09-3287. Epub 2003 Nov 26. Blood. 2004. PMID: 14644997 Free article.
Mutations in GATA2 are rare in juvenile myelomonocytic leukemia.
Stieglitz E, Liu YL, Emanuel PD, Castleberry RP, Cooper TM, Shannon KM, Loh ML. Stieglitz E, et al. Among authors: shannon km. Blood. 2014 Feb 27;123(9):1426-7. doi: 10.1182/blood-2013-11-531079. Blood. 2014. PMID: 24578498 Free PMC article. No abstract available.
358 results