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Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis.
Tannour-Louet M, York B, Tang K, Stashi E, Bouguerra H, Zhou S, Yu H, Wong LJ, Stevens RD, Xu J, Newgard CB, O'Malley BW, Louet JF. Tannour-Louet M, et al. Among authors: louet jf. Mol Endocrinol. 2014 Oct;28(10):1707-18. doi: 10.1210/me.2014-1083. Epub 2014 Aug 22. Mol Endocrinol. 2014. PMID: 25148457 Free PMC article.
The coactivator SRC-1 is an essential coordinator of hepatic glucose production.
Louet JF, Chopra AR, Sagen JV, An J, York B, Tannour-Louet M, Saha PK, Stevens RD, Wenner BR, Ilkayeva OR, Bain JR, Zhou S, DeMayo F, Xu J, Newgard CB, O'Malley BW. Louet JF, et al. Cell Metab. 2010 Dec 1;12(6):606-18. doi: 10.1016/j.cmet.2010.11.009. Cell Metab. 2010. PMID: 21109193 Free PMC article.
Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy.
York B, Reineke EL, Sagen JV, Nikolai BC, Zhou S, Louet JF, Chopra AR, Chen X, Reed G, Noebels J, Adesina AM, Yu H, Wong LJ, Tsimelzon A, Hilsenbeck S, Stevens RD, Wenner BR, Ilkayeva O, Xu J, Newgard CB, O'Malley BW. York B, et al. Among authors: louet jf. Cell Metab. 2012 May 2;15(5):752-63. doi: 10.1016/j.cmet.2012.03.020. Cell Metab. 2012. PMID: 22560224 Free PMC article.
18 results