Leapman RD - Search Results

1

Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils.

Paravastu AK, Leapman RD, Yau WM, Tycko R. Paravastu AK, et al. Among authors: leapman rd. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18349-54. doi: 10.1073/pnas.0806270105. Epub 2008 Nov 17. Proc Natl Acad Sci U S A. 2008. PMID: 19015532 Free PMC article.

2

Single kinesin molecules crossbridge microtubules in vitro.

Andrews SB, Gallant PE, Leapman RD, Schnapp BJ, Reese TS. Andrews SB, et al. Among authors: leapman rd. Proc Natl Acad Sci U S A. 1993 Jul 15;90(14):6503-7. doi: 10.1073/pnas.90.14.6503. Proc Natl Acad Sci U S A. 1993. PMID: 8341662 Free PMC article.

3

Phosphorylation and subunit organization of axonal neurofilaments determined by scanning transmission electron microscopy.

Leapman RD, Gallant PE, Reese TS, Andrews SB. Leapman RD, et al. Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):7820-4. doi: 10.1073/pnas.94.15.7820. Proc Natl Acad Sci U S A. 1997. PMID: 9223270 Free PMC article.

4

Multiple quantum solid-state NMR indicates a parallel, not antiparallel, organization of beta-sheets in Alzheimer's beta-amyloid fibrils.

Antzutkin ON, Balbach JJ, Leapman RD, Rizzo NW, Reed J, Tycko R. Antzutkin ON, et al. Among authors: leapman rd. Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13045-50. doi: 10.1073/pnas.230315097. Proc Natl Acad Sci U S A. 2000. PMID: 11069287 Free PMC article.

5

Amyloid fibril formation by A beta 16-22, a seven-residue fragment of the Alzheimer's beta-amyloid peptide, and structural characterization by solid state NMR.

Balbach JJ, Ishii Y, Antzutkin ON, Leapman RD, Rizzo NW, Dyda F, Reed J, Tycko R. Balbach JJ, et al. Among authors: leapman rd. Biochemistry. 2000 Nov 14;39(45):13748-59. doi: 10.1021/bi0011330. Biochemistry. 2000. PMID: 11076514

6

Oligomeric structure of virion-associated and soluble forms of the simian immunodeficiency virus envelope protein in the prefusion activated conformation.

Center RJ, Schuck P, Leapman RD, Arthur LO, Earl PL, Moss B, Lebowitz J. Center RJ, et al. Among authors: leapman rd. Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):14877-82. doi: 10.1073/pnas.261573898. Proc Natl Acad Sci U S A. 2001. PMID: 11752436 Free PMC article.

7

A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR.

Petkova AT, Ishii Y, Balbach JJ, Antzutkin ON, Leapman RD, Delaglio F, Tycko R. Petkova AT, et al. Among authors: leapman rd. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16742-7. doi: 10.1073/pnas.262663499. Epub 2002 Dec 12. Proc Natl Acad Sci U S A. 2002. PMID: 12481027 Free PMC article.

8

Supramolecular structural constraints on Alzheimer's beta-amyloid fibrils from electron microscopy and solid-state nuclear magnetic resonance.

Antzutkin ON, Leapman RD, Balbach JJ, Tycko R. Antzutkin ON, et al. Among authors: leapman rd. Biochemistry. 2002 Dec 24;41(51):15436-50. doi: 10.1021/bi0204185. Biochemistry. 2002. PMID: 12484785

9

Solid state NMR reveals a pH-dependent antiparallel beta-sheet registry in fibrils formed by a beta-amyloid peptide.

Petkova AT, Buntkowsky G, Dyda F, Leapman RD, Yau WM, Tycko R. Petkova AT, et al. Among authors: leapman rd. J Mol Biol. 2004 Jan 2;335(1):247-60. doi: 10.1016/j.jmb.2003.10.044. J Mol Biol. 2004. PMID: 14659754

10

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils.

Petkova AT, Leapman RD, Guo Z, Yau WM, Mattson MP, Tycko R. Petkova AT, et al. Among authors: leapman rd. Science. 2005 Jan 14;307(5707):262-5. doi: 10.1126/science.1105850. Science. 2005. PMID: 15653506

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