Bec G - Search Results

1

Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (S-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants.

Radi M, Maga G, Alongi M, Angeli L, Samuele A, Zanoli S, Bellucci L, Tafi A, Casaluce G, Giorgi G, Armand-Ugon M, Gonzalez E, Esté JA, Baltzinger M, Bec G, Dumas P, Ennifar E, Botta M. Radi M, et al. Among authors: bec g. J Med Chem. 2009 Feb 12;52(3):840-51. doi: 10.1021/jm801330n. J Med Chem. 2009. PMID: 19140683

2

Crystal structure of HIV-1 reverse transcriptase bound to a non-nucleoside inhibitor with a novel mechanism of action.

Freisz S, Bec G, Radi M, Wolff P, Crespan E, Angeli L, Dumas P, Maga G, Botta M, Ennifar E. Freisz S, et al. Among authors: bec g. Angew Chem Int Ed Engl. 2010 Mar 1;49(10):1805-8. doi: 10.1002/anie.200905651. Angew Chem Int Ed Engl. 2010. PMID: 20135654 No abstract available.

3

Thermodynamics of HIV-1 reverse transcriptase in action elucidates the mechanism of action of non-nucleoside inhibitors.

Bec G, Meyer B, Gerard MA, Steger J, Fauster K, Wolff P, Burnouf D, Micura R, Dumas P, Ennifar E. Bec G, et al. J Am Chem Soc. 2013 Jul 3;135(26):9743-52. doi: 10.1021/ja4018418. Epub 2013 Jun 18. J Am Chem Soc. 2013. PMID: 23742167

4

switchSENSE Technology for Analysis of DNA Polymerase Kinetics.

Bec G, Ennifar E. Bec G, et al. Methods Mol Biol. 2021;2247:145-153. doi: 10.1007/978-1-0716-1126-5_8. Methods Mol Biol. 2021. PMID: 33301116

5

kinITC: a new method for obtaining joint thermodynamic and kinetic data by isothermal titration calorimetry.

Burnouf D, Ennifar E, Guedich S, Puffer B, Hoffmann G, Bec G, Disdier F, Baltzinger M, Dumas P. Burnouf D, et al. Among authors: bec g. J Am Chem Soc. 2012 Jan 11;134(1):559-65. doi: 10.1021/ja209057d. Epub 2011 Dec 16. J Am Chem Soc. 2012. PMID: 22126339

6

Multianalytical Study of the Binding between a Small Chiral Molecule and a DNA Aptamer: Evidence for Asymmetric Steric Effect upon 3'- versus 5'-End Sequence Modification.

Challier L, Miranda-Castro R, Barbe B, Fave C, Limoges B, Peyrin E, Ravelet C, Fiore E, Labbé P, Coche-Guérente L, Ennifar E, Bec G, Dumas P, Mavré F, Noël V. Challier L, et al. Among authors: bec g. Anal Chem. 2016 Dec 6;88(23):11963-11971. doi: 10.1021/acs.analchem.6b04046. Epub 2016 Nov 16. Anal Chem. 2016. PMID: 27934108

7

Quantitative and predictive model of kinetic regulation by E. coli TPP riboswitches.

Guedich S, Puffer-Enders B, Baltzinger M, Hoffmann G, Da Veiga C, Jossinet F, Thore S, Bec G, Ennifar E, Burnouf D, Dumas P. Guedich S, et al. Among authors: bec g. RNA Biol. 2016;13(4):373-90. doi: 10.1080/15476286.2016.1142040. Epub 2016 Mar 1. RNA Biol. 2016. PMID: 26932506 Free PMC article.

8

Native ESI Mass Spectrometry Can Help to Avoid Wrong Interpretations from Isothermal Titration Calorimetry in Difficult Situations.

Wolff P, Da Veiga C, Ennifar E, Bec G, Guichard G, Burnouf D, Dumas P. Wolff P, et al. Among authors: bec g. J Am Soc Mass Spectrom. 2017 Feb;28(2):347-357. doi: 10.1007/s13361-016-1534-6. Epub 2016 Dec 12. J Am Soc Mass Spectrom. 2017. PMID: 27957716 Free PMC article.

9

Extending ITC to Kinetics with kinITC.

Dumas P, Ennifar E, Da Veiga C, Bec G, Palau W, Di Primo C, Piñeiro A, Sabin J, Muñoz E, Rial J. Dumas P, et al. Among authors: bec g. Methods Enzymol. 2016;567:157-80. doi: 10.1016/bs.mie.2015.08.026. Epub 2015 Oct 30. Methods Enzymol. 2016. PMID: 26794354

10

Biophysical Studies of the Binding of Viral RNA with the 80S Ribosome Using switchSENSE.

Schenckbecher E, Bec G, Sakamoto T, Meyer B, Ennifar E. Schenckbecher E, et al. Among authors: bec g. Methods Mol Biol. 2021;2263:341-350. doi: 10.1007/978-1-0716-1197-5_15. Methods Mol Biol. 2021. PMID: 33877606

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