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Modulation of DNA methylation by a sesquiterpene lactone parthenolide.
Liu Z, Liu S, Xie Z, Pavlovicz RE, Wu J, Chen P, Aimiuwu J, Pang J, Bhasin D, Neviani P, Fuchs JR, Plass C, Li PK, Li C, Huang TH, Wu LC, Rush L, Wang H, Perrotti D, Marcucci G, Chan KK. Liu Z, et al. Among authors: neviani p. J Pharmacol Exp Ther. 2009 May;329(2):505-14. doi: 10.1124/jpet.108.147934. Epub 2009 Feb 6. J Pharmacol Exp Ther. 2009. PMID: 19201992 Free PMC article.
Targeting AML1/ETO-histone deacetylase repressor complex: a novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells.
Liu S, Klisovic RB, Vukosavljevic T, Yu J, Paschka P, Huynh L, Pang J, Neviani P, Liu Z, Blum W, Chan KK, Perrotti D, Marcucci G. Liu S, et al. Among authors: neviani p. J Pharmacol Exp Ther. 2007 Jun;321(3):953-60. doi: 10.1124/jpet.106.118406. Epub 2007 Mar 26. J Pharmacol Exp Ther. 2007. PMID: 17389244
SETting OP449 into the PP2A-activating drug family.
Neviani P, Perrotti D. Neviani P, et al. Clin Cancer Res. 2014 Apr 15;20(8):2026-8. doi: 10.1158/1078-0432.CCR-14-0166. Epub 2014 Mar 14. Clin Cancer Res. 2014. PMID: 24634375 Free PMC article.
Protein phosphatase 2A: a target for anticancer therapy.
Perrotti D, Neviani P. Perrotti D, et al. Among authors: neviani p. Lancet Oncol. 2013 May;14(6):e229-38. doi: 10.1016/S1470-2045(12)70558-2. Lancet Oncol. 2013. PMID: 23639323 Free PMC article. Review.
The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein.
Neviani P, Santhanam R, Trotta R, Notari M, Blaser BW, Liu S, Mao H, Chang JS, Galietta A, Uttam A, Roy DC, Valtieri M, Bruner-Klisovic R, Caligiuri MA, Bloomfield CD, Marcucci G, Perrotti D. Neviani P, et al. Cancer Cell. 2005 Nov;8(5):355-68. doi: 10.1016/j.ccr.2005.10.015. Cancer Cell. 2005. PMID: 16286244 Free article.
The PP2A inhibitor SET regulates natural killer cell IFN-gamma production.
Trotta R, Ciarlariello D, Dal Col J, Allard J 2nd, Neviani P, Santhanam R, Mao H, Becknell B, Yu J, Ferketich AK, Thomas B, Modi A, Blaser BW, Perrotti D, Caligiuri MA. Trotta R, et al. Among authors: neviani p. J Exp Med. 2007 Oct 1;204(10):2397-405. doi: 10.1084/jem.20070419. Epub 2007 Sep 17. J Exp Med. 2007. PMID: 17875674 Free PMC article.
51 results