Spiekermann K - Search Results

1

NPM1 but not FLT3-ITD mutations predict early blast cell clearance and CR rate in patients with normal karyotype AML (NK-AML) or high-risk myelodysplastic syndrome (MDS).

Schneider F, Hoster E, Unterhalt M, Schneider S, Dufour A, Benthaus T, Mellert G, Zellmeier E, Bohlander SK, Feuring-Buske M, Buske C, Braess J, Fritsch S, Heinecke A, Sauerland MC, Berdel WE, Buechner T, Woermann BJ, Hiddemann W, Spiekermann K. Schneider F, et al. Among authors: spiekermann k. Blood. 2009 May 21;113(21):5250-3. doi: 10.1182/blood-2008-09-172668. Epub 2009 Mar 11. Blood. 2009. PMID: 19279329 Free article.

2

Combination chemotherapy with CHOP for recurrent thrombotic thrombocytopenic purpura.

Spiekermann K, Wörmann B, Rumpf KW, Hiddemann W. Spiekermann K, et al. Br J Haematol. 1997 Jun;97(3):544-6. doi: 10.1046/j.1365-2141.1997.1022918.x. Br J Haematol. 1997. PMID: 9207396 Free article.

3

Expression of granulocyte colony-stimulating factor- and granulocyte-macrophage colony-stimulating factor-associated signal transduction proteins of the JAK/STAT pathway in normal granulopoiesis and in blast cells of acute myelogenous leukemia.

Biethahn S, Alves F, Wilde S, Hiddemann W, Spiekermann K. Biethahn S, et al. Among authors: spiekermann k. Exp Hematol. 1999 May;27(5):885-94. doi: 10.1016/s0301-472x(99)00017-x. Exp Hematol. 1999. PMID: 10340405 Free article.

4

Constitutive activation of STAT transcription factors in acute myelogenous leukemia.

Spiekermann K, Biethahn S, Wilde S, Hiddemann W, Alves F. Spiekermann K, et al. Eur J Haematol. 2001 Aug;67(2):63-71. Eur J Haematol. 2001. PMID: 11722592

5

Constitutive activation of STAT3 and STAT5 is induced by leukemic fusion proteins with protein tyrosine kinase activity and is sufficient for transformation of hematopoietic precursor cells.

Spiekermann K, Pau M, Schwab R, Schmieja K, Franzrahe S, Hiddemann W. Spiekermann K, et al. Exp Hematol. 2002 Mar;30(3):262-71. doi: 10.1016/s0301-472x(01)00787-1. Exp Hematol. 2002. PMID: 11882364 Free article.

6

Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells.

Buske C, Feuring-Buske M, Abramovich C, Spiekermann K, Eaves CJ, Coulombel L, Sauvageau G, Hogge DE, Humphries RK. Buske C, et al. Among authors: spiekermann k. Blood. 2002 Aug 1;100(3):862-8. doi: 10.1182/blood-2002-01-0220. Blood. 2002. PMID: 12130496 Free article.

7

The protein tyrosine kinase inhibitor SU5614 inhibits VEGF-induced endothelial cell sprouting and induces growth arrest and apoptosis by inhibition of c-kit in AML cells.

Spiekermann K, Faber F, Voswinckel R, Hiddemann W. Spiekermann K, et al. Exp Hematol. 2002 Jul;30(7):767-73. doi: 10.1016/s0301-472x(02)00837-8. Exp Hematol. 2002. PMID: 12135675 Free article.

8

A new and recurrent activating length mutation in exon 20 of the FLT3 gene in acute myeloid leukemia.

Spiekermann K, Bagrintseva K, Schoch C, Haferlach T, Hiddemann W, Schnittger S. Spiekermann K, et al. Blood. 2002 Nov 1;100(9):3423-5. doi: 10.1182/blood-2002-03-0953. Blood. 2002. PMID: 12384447 Free article.

9

The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3.

Spiekermann K, Dirschinger RJ, Schwab R, Bagrintseva K, Faber F, Buske C, Schnittger S, Kelly LM, Gilliland DG, Hiddemann W. Spiekermann K, et al. Blood. 2003 Feb 15;101(4):1494-504. doi: 10.1182/blood-2002-04-1045. Epub 2002 Oct 24. Blood. 2003. PMID: 12406902 Free article.

10

Overexpression and constitutive activation of FLT3 induces STAT5 activation in primary acute myeloid leukemia blast cells.

Spiekermann K, Bagrintseva K, Schwab R, Schmieja K, Hiddemann W. Spiekermann K, et al. Clin Cancer Res. 2003 Jun;9(6):2140-50. Clin Cancer Res. 2003. PMID: 12796379

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