Ingelman-Sundberg M - Search Results

1

Xenobiotic-metabolizing enzymes and transporters in the normal human brain: regional and cellular mapping as a basis for putative roles in cerebral function.

Dutheil F, Dauchy S, Diry M, Sazdovitch V, Cloarec O, Mellottée L, Bièche I, Ingelman-Sundberg M, Flinois JP, de Waziers I, Beaune P, Declèves X, Duyckaerts C, Loriot MA. Dutheil F, et al. Drug Metab Dispos. 2009 Jul;37(7):1528-38. doi: 10.1124/dmd.109.027011. Epub 2009 Apr 9. Drug Metab Dispos. 2009. PMID: 19359404

2

Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism.

Westlind-Johnsson A, Malmebo S, Johansson A, Otter C, Andersson TB, Johansson I, Edwards RJ, Boobis AR, Ingelman-Sundberg M. Westlind-Johnsson A, et al. Drug Metab Dispos. 2003 Jun;31(6):755-61. doi: 10.1124/dmd.31.6.755. Drug Metab Dispos. 2003. PMID: 12756208

3

CYP2B6 and CYP2C19 as the major enzymes responsible for the metabolism of selegiline, a drug used in the treatment of Parkinson's disease, as revealed from experiments with recombinant enzymes.

Hidestrand M, Oscarson M, Salonen JS, Nyman L, Pelkonen O, Turpeinen M, Ingelman-Sundberg M. Hidestrand M, et al. Drug Metab Dispos. 2001 Nov;29(11):1480-4. Drug Metab Dispos. 2001. PMID: 11602525

4

Generation of mice transgenic for human CYP2C18 and CYP2C19: characterization of the sexually dimorphic gene and enzyme expression.

Löfgren S, Baldwin RM, Hiratsuka M, Lindqvist A, Carlberg A, Sim SC, Schülke M, Snait M, Edenro A, Fransson-Steen R, Terelius Y, Ingelman-Sundberg M. Löfgren S, et al. Drug Metab Dispos. 2008 May;36(5):955-62. doi: 10.1124/dmd.107.019349. Epub 2008 Feb 14. Drug Metab Dispos. 2008. PMID: 18276835

5

CYP3A4 catalytic activity is induced in confluent Huh7 hepatoma cells.

Sivertsson L, Ek M, Darnell M, Edebert I, Ingelman-Sundberg M, Neve EP. Sivertsson L, et al. Drug Metab Dispos. 2010 Jun;38(6):995-1002. doi: 10.1124/dmd.110.032367. Epub 2010 Mar 16. Drug Metab Dispos. 2010. PMID: 20233841

6

Characterization of human cytochrome P450s involved in the bioactivation of clozapine.

Dragovic S, Gunness P, Ingelman-Sundberg M, Vermeulen NP, Commandeur JN. Dragovic S, et al. Drug Metab Dispos. 2013 Mar;41(3):651-8. doi: 10.1124/dmd.112.050484. Epub 2013 Jan 7. Drug Metab Dispos. 2013. PMID: 23297297

7

Potential role of epigenetic mechanisms in the regulation of drug metabolism and transport.

Ingelman-Sundberg M, Zhong XB, Hankinson O, Beedanagari S, Yu AM, Peng L, Osawa Y. Ingelman-Sundberg M, et al. Drug Metab Dispos. 2013 Oct;41(10):1725-31. doi: 10.1124/dmd.113.053157. Epub 2013 Aug 5. Drug Metab Dispos. 2013. PMID: 23918665 Free PMC article.

8

An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant.

Andersson TB, Sjöberg H, Hoffmann KJ, Boobis AR, Watts P, Edwards RJ, Lake BG, Price RJ, Renwick AB, Gómez-Lechón MJ, Castell JV, Ingelman-Sundberg M, Hidestrand M, Goldfarb PS, Lewis DF, Corcos L, Guillouzo A, Taavitsainen P, Pelkonen O. Andersson TB, et al. Drug Metab Dispos. 2001 May;29(5):712-20. Drug Metab Dispos. 2001. PMID: 11302938

9

Regulation of human CYP2C18 and CYP2C19 in transgenic mice: influence of castration, testosterone, and growth hormone.

Löfgren S, Baldwin RM, Carlerös M, Terelius Y, Fransson-Steen R, Mwinyi J, Waxman DJ, Ingelman-Sundberg M. Löfgren S, et al. Drug Metab Dispos. 2009 Jul;37(7):1505-12. doi: 10.1124/dmd.109.026963. Epub 2009 Apr 1. Drug Metab Dispos. 2009. PMID: 19339376 Free PMC article.

10

Characterization of the novel defective CYP2C9*24 allele.

Herman D, Dolzan V, Ingelman-Sundberg M. Herman D, et al. Drug Metab Dispos. 2007 Jun;35(6):831-4. doi: 10.1124/dmd.106.013722. Epub 2007 Mar 1. Drug Metab Dispos. 2007. PMID: 17332144

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