Telliez JB - Search Results

1

Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-alpha production in human whole blood.

Wu J, Green N, Hotchandani R, Hu Y, Condon J, Huang A, Kaila N, Li HQ, Guler S, Li W, Tam SY, Wang Q, Pelker J, Marusic S, Hsu S, Perry Hall J, Telliez JB, Cui J, Lin LL. Wu J, et al. Among authors: telliez jb. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3485-8. doi: 10.1016/j.bmcl.2009.05.009. Epub 2009 May 7. Bioorg Med Chem Lett. 2009. PMID: 19464884

2

Engagement of tumor necrosis factor (TNF) receptor 1 leads to ATF-2- and p38 mitogen-activated protein kinase-dependent TNF-alpha gene expression.

Brinkman BM, Telliez JB, Schievella AR, Lin LL, Goldfeld AE. Brinkman BM, et al. Among authors: telliez jb. J Biol Chem. 1999 Oct 22;274(43):30882-6. doi: 10.1074/jbc.274.43.30882. J Biol Chem. 1999. PMID: 10521481 Free article.

3

LRDD, a novel leucine rich repeat and death domain containing protein.

Telliez JB, Bean KM, Lin LL. Telliez JB, et al. Biochim Biophys Acta. 2000 May 23;1478(2):280-8. doi: 10.1016/s0167-4838(00)00029-7. Biochim Biophys Acta. 2000. PMID: 10825539

4

Mutational analysis and NMR studies of the death domain of the tumor necrosis factor receptor-1.

Telliez JB, Xu GY, Woronicz JD, Hsu S, Wu JL, Lin L, Sukits SF, Powers R, Lin LL. Telliez JB, et al. J Mol Biol. 2000 Jul 28;300(5):1323-33. doi: 10.1006/jmbi.2000.3899. J Mol Biol. 2000. PMID: 10903872

5

Solution structure of N-TRADD and characterization of the interaction of N-TRADD and C-TRAF2, a key step in the TNFR1 signaling pathway.

Tsao DH, McDonagh T, Telliez JB, Hsu S, Malakian K, Xu GY, Lin LL. Tsao DH, et al. Among authors: telliez jb. Mol Cell. 2000 Jun;5(6):1051-7. doi: 10.1016/s1097-2765(00)80270-1. Mol Cell. 2000. PMID: 10911999 Free article.

6

Inhibition of Tpl2 kinase and TNF-alpha production with 1,7-naphthyridine-3-carbonitriles: synthesis and structure-activity relationships.

Gavrin LK, Green N, Hu Y, Janz K, Kaila N, Li HQ, Tam SY, Thomason JR, Gopalsamy A, Ciszewski G, Cuozzo JW, Hall JP, Hsu S, Telliez JB, Lin LL. Gavrin LK, et al. Among authors: telliez jb. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5288-92. doi: 10.1016/j.bmcl.2005.08.029. Epub 2005 Sep 13. Bioorg Med Chem Lett. 2005. PMID: 16165349

7

MAPKAP kinase 2-deficient mice are resistant to collagen-induced arthritis.

Hegen M, Gaestel M, Nickerson-Nutter CL, Lin LL, Telliez JB. Hegen M, et al. Among authors: telliez jb. J Immunol. 2006 Aug 1;177(3):1913-7. doi: 10.4049/jimmunol.177.3.1913. J Immunol. 2006. PMID: 16849504

8

Inhibition of Tpl2 kinase and TNFalpha production with quinoline-3-carbonitriles for the treatment of rheumatoid arthritis.

Hu Y, Green N, Gavrin LK, Janz K, Kaila N, Li HQ, Thomason JR, Cuozzo JW, Hall JP, Hsu S, Nickerson-Nutter C, Telliez JB, Lin LL, Tam S. Hu Y, et al. Among authors: telliez jb. Bioorg Med Chem Lett. 2006 Dec 1;16(23):6067-72. doi: 10.1016/j.bmcl.2006.08.102. Epub 2006 Sep 14. Bioorg Med Chem Lett. 2006. PMID: 16973359

9

Identification of a novel class of selective Tpl2 kinase inhibitors: 4-Alkylamino-[1,7]naphthyridine-3-carbonitriles.

Kaila N, Green N, Li HQ, Hu Y, Janz K, Gavrin LK, Thomason J, Tam S, Powell D, Cuozzo J, Hall JP, Telliez JB, Hsu S, Nickerson-Nutter C, Wang Q, Lin LL. Kaila N, et al. Among authors: telliez jb. Bioorg Med Chem. 2007 Oct 1;15(19):6425-42. doi: 10.1016/j.bmc.2007.06.054. Epub 2007 Jul 4. Bioorg Med Chem. 2007. PMID: 17664070

10

Inhibitors of tumor progression loci-2 (Tpl2) kinase and tumor necrosis factor alpha (TNF-alpha) production: selectivity and in vivo antiinflammatory activity of novel 8-substituted-4-anilino-6-aminoquinoline-3-carbonitriles.

Green N, Hu Y, Janz K, Li HQ, Kaila N, Guler S, Thomason J, Joseph-McCarthy D, Tam SY, Hotchandani R, Wu J, Huang A, Wang Q, Leung L, Pelker J, Marusic S, Hsu S, Telliez JB, Hall JP, Cuozzo JW, Lin LL. Green N, et al. Among authors: telliez jb. J Med Chem. 2007 Sep 20;50(19):4728-45. doi: 10.1021/jm070436q. Epub 2007 Aug 23. J Med Chem. 2007. PMID: 17715908

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