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Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition.
Luciani A, Villella VR, Esposito S, Brunetti-Pierri N, Medina D, Settembre C, Gavina M, Pulze L, Giardino I, Pettoello-Mantovani M, D'Apolito M, Guido S, Masliah E, Spencer B, Quaratino S, Raia V, Ballabio A, Maiuri L. Luciani A, et al. Nat Cell Biol. 2010 Sep;12(9):863-75. doi: 10.1038/ncb2090. Epub 2010 Aug 15. Nat Cell Biol. 2010. PMID: 20711182
Cystic fibrosis: a disorder with defective autophagy.
Luciani A, Villella VR, Esposito S, Brunetti-Pierri N, Medina DL, Settembre C, Gavina M, Raia V, Ballabio A, Maiuri L. Luciani A, et al. Autophagy. 2011 Jan;7(1):104-6. doi: 10.4161/auto.7.1.13987. Epub 2011 Jan 1. Autophagy. 2011. PMID: 21048426
Nebulized hyaluronan ameliorates lung inflammation in cystic fibrosis mice.
Gavina M, Luciani A, Villella VR, Esposito S, Ferrari E, Bressani I, Casale A, Bruscia EM, Maiuri L, Raia V. Gavina M, et al. Among authors: luciani a. Pediatr Pulmonol. 2013 Aug;48(8):761-71. doi: 10.1002/ppul.22637. Epub 2012 Jul 23. Pediatr Pulmonol. 2013. PMID: 22825912
Genistein antagonizes gliadin-induced CFTR malfunction in models of celiac disease.
Esposito S, Villella VR, Ferrari E, Monzani R, Tosco A, Rossin F, D'Eletto M, Castaldo A, Luciani A, Silano M, Bona G, Marseglia GL, Romani L, Piacentini M, Raia V, Kroemer G, Maiuri L. Esposito S, et al. Among authors: luciani a. Aging (Albany NY). 2019 Apr 12;11(7):2003-2019. doi: 10.18632/aging.101888. Aging (Albany NY). 2019. PMID: 30981209 Free PMC article.
Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator.
Luciani A, Villella VR, Esposito S, Gavina M, Russo I, Silano M, Guido S, Pettoello-Mantovani M, Carnuccio R, Scholte B, De Matteis A, Maiuri MC, Raia V, Luini A, Kroemer G, Maiuri L. Luciani A, et al. Autophagy. 2012 Nov;8(11):1657-72. doi: 10.4161/auto.21483. Epub 2012 Aug 9. Autophagy. 2012. PMID: 22874563 Free PMC article.
A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease.
Villella VR, Venerando A, Cozza G, Esposito S, Ferrari E, Monzani R, Spinella MC, Oikonomou V, Renga G, Tosco A, Rossin F, Guido S, Silano M, Garaci E, Chao YK, Grimm C, Luciani A, Romani L, Piacentini M, Raia V, Kroemer G, Maiuri L. Villella VR, et al. Among authors: luciani a. EMBO J. 2019 Jan 15;38(2):e100101. doi: 10.15252/embj.2018100101. Epub 2018 Nov 29. EMBO J. 2019. PMID: 30498130 Free PMC article.
575 results