Liu JY - Search Results

1

Sorafenib has soluble epoxide hydrolase inhibitory activity, which contributes to its effect profile in vivo.

Liu JY, Park SH, Morisseau C, Hwang SH, Hammock BD, Weiss RH. Liu JY, et al. Mol Cancer Ther. 2009 Aug;8(8):2193-203. doi: 10.1158/1535-7163.MCT-09-0119. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671760 Free PMC article.

2

Orally bioavailable potent soluble epoxide hydrolase inhibitors.

Hwang SH, Tsai HJ, Liu JY, Morisseau C, Hammock BD. Hwang SH, et al. Among authors: liu jy. J Med Chem. 2007 Aug 9;50(16):3825-40. doi: 10.1021/jm070270t. Epub 2007 Jul 6. J Med Chem. 2007. PMID: 17616115 Free PMC article.

3

Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation.

Liu JY, Tsai HJ, Hwang SH, Jones PD, Morisseau C, Hammock BD. Liu JY, et al. Br J Pharmacol. 2009 Jan;156(2):284-96. doi: 10.1111/j.1476-5381.2008.00009.x. Epub 2009 Jan 13. Br J Pharmacol. 2009. PMID: 19154430 Free PMC article.

4

Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: Insight gained using metabolomic approaches.

Li N, Liu JY, Timofeyev V, Qiu H, Hwang SH, Tuteja D, Lu L, Yang J, Mochida H, Low R, Hammock BD, Chiamvimonvat N. Li N, et al. Among authors: liu jy. J Mol Cell Cardiol. 2009 Dec;47(6):835-45. doi: 10.1016/j.yjmcc.2009.08.017. Epub 2009 Aug 28. J Mol Cell Cardiol. 2009. PMID: 19716829 Free PMC article.

5

Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model.

Liu JY, Yang J, Inceoglu B, Qiu H, Ulu A, Hwang SH, Chiamvimonvat N, Hammock BD. Liu JY, et al. Biochem Pharmacol. 2010 Mar 15;79(6):880-7. doi: 10.1016/j.bcp.2009.10.025. Epub 2009 Nov 5. Biochem Pharmacol. 2010. PMID: 19896470 Free PMC article.

6

Soluble epoxide hydrolase inhibitors and heart failure.

Qiu H, Li N, Liu JY, Harris TR, Hammock BD, Chiamvimonvat N. Qiu H, et al. Among authors: liu jy. Cardiovasc Ther. 2011 Apr;29(2):99-111. doi: 10.1111/j.1755-5922.2010.00150.x. Cardiovasc Ther. 2011. PMID: 20433684 Free PMC article. Review.

7

1-Aryl-3-(1-acylpiperidin-4-yl)urea inhibitors of human and murine soluble epoxide hydrolase: structure-activity relationships, pharmacokinetics, and reduction of inflammatory pain.

Rose TE, Morisseau C, Liu JY, Inceoglu B, Jones PD, Sanborn JR, Hammock BD. Rose TE, et al. Among authors: liu jy. J Med Chem. 2010 Oct 14;53(19):7067-75. doi: 10.1021/jm100691c. J Med Chem. 2010. PMID: 20812725 Free PMC article.

8

Metabolic profiling of murine plasma reveals an unexpected biomarker in rofecoxib-mediated cardiovascular events.

Liu JY, Li N, Yang J, Li N, Qiu H, Ai D, Chiamvimonvat N, Zhu Y, Hammock BD. Liu JY, et al. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):17017-22. doi: 10.1073/pnas.1011278107. Epub 2010 Sep 13. Proc Natl Acad Sci U S A. 2010. PMID: 20837537 Free PMC article.

9

Incorporation of piperazino functionality into 1,3-disubstituted urea as the tertiary pharmacophore affording potent inhibitors of soluble epoxide hydrolase with improved pharmacokinetic properties.

Huang SX, Li HY, Liu JY, Morisseau C, Hammock BD, Long YQ. Huang SX, et al. Among authors: liu jy. J Med Chem. 2010 Dec 9;53(23):8376-86. doi: 10.1021/jm101087u. Epub 2010 Nov 11. J Med Chem. 2010. PMID: 21070033 Free PMC article.

10

Use of metabolomic profiling in the study of arachidonic acid metabolism in cardiovascular disease.

Li N, Liu JY, Qiu H, Harris TR, Sirish P, Hammock BD, Chiamvimonvat N. Li N, et al. Among authors: liu jy. Congest Heart Fail. 2011 Jan-Feb;17(1):42-6. doi: 10.1111/j.1751-7133.2010.00209.x. Epub 2011 Jan 27. Congest Heart Fail. 2011. PMID: 21272227 Free PMC article. Review.

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