Mandel RJ - Search Results

1

Tight Long-term dynamic doxycycline responsive nigrostriatal GDNF using a single rAAV vector.

Manfredsson FP, Burger C, Rising AC, Zuobi-Hasona K, Sullivan LF, Lewin AS, Huang J, Piercefield E, Muzyczka N, Mandel RJ. Manfredsson FP, et al. Among authors: mandel rj. Mol Ther. 2009 Nov;17(11):1857-67. doi: 10.1038/mt.2009.196. Epub 2009 Aug 25. Mol Ther. 2009. PMID: 19707186 Free PMC article.

2

RNA knockdown as a potential therapeutic strategy in Parkinson's disease.

Manfredsson FP, Lewin AS, Mandel RJ. Manfredsson FP, et al. Among authors: mandel rj. Gene Ther. 2006 Mar;13(6):517-24. doi: 10.1038/sj.gt.3302669. Gene Ther. 2006. PMID: 16267570 Review.

3

Neuroprotective potential of pleiotrophin overexpression in the striatonigral pathway compared with overexpression in both the striatonigral and nigrostriatal pathways.

Gombash SE, Manfredsson FP, Mandel RJ, Collier TJ, Fischer DL, Kemp CJ, Kuhn NM, Wohlgenant SL, Fleming SM, Sortwell CE. Gombash SE, et al. Among authors: mandel rj. Gene Ther. 2014 Jul;21(7):682-93. doi: 10.1038/gt.2014.42. Epub 2014 May 8. Gene Ther. 2014. PMID: 24807806 Free PMC article.

4

Circulating anti-wild-type adeno-associated virus type 2 (AAV2) antibodies inhibit recombinant AAV2 (rAAV2)-mediated, but not rAAV5-mediated, gene transfer in the brain.

Peden CS, Burger C, Muzyczka N, Mandel RJ. Peden CS, et al. Among authors: mandel rj. J Virol. 2004 Jun;78(12):6344-59. doi: 10.1128/JVI.78.12.6344-6359.2004. J Virol. 2004. PMID: 15163728 Free PMC article.

5

Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system.

Burger C, Gorbatyuk OS, Velardo MJ, Peden CS, Williams P, Zolotukhin S, Reier PJ, Mandel RJ, Muzyczka N. Burger C, et al. Among authors: mandel rj. Mol Ther. 2004 Aug;10(2):302-17. doi: 10.1016/j.ymthe.2004.05.024. Mol Ther. 2004. PMID: 15294177 Free article.

6

Systemic mannitol-induced hyperosmolality amplifies rAAV2-mediated striatal transduction to a greater extent than local co-infusion.

Burger C, Nguyen FN, Deng J, Mandel RJ. Burger C, et al. Among authors: mandel rj. Mol Ther. 2005 Feb;11(2):327-31. doi: 10.1016/j.ymthe.2004.08.031. Mol Ther. 2005. PMID: 15668145 Free article.

7

Recombinant adeno-associated viral vectors in the nervous system.

Burger C, Nash K, Mandel RJ. Burger C, et al. Among authors: mandel rj. Hum Gene Ther. 2005 Jul;16(7):781-91. doi: 10.1089/hum.2005.16.781. Hum Gene Ther. 2005. PMID: 16000060 Review.

8

Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice.

Rodriguez-Lebron E, Denovan-Wright EM, Nash K, Lewin AS, Mandel RJ. Rodriguez-Lebron E, et al. Among authors: mandel rj. Mol Ther. 2005 Oct;12(4):618-33. doi: 10.1016/j.ymthe.2005.05.006. Mol Ther. 2005. PMID: 16019264 Free PMC article.

9

Recombinant adeno-associated viral vectors as therapeutic agents to treat neurological disorders.

Mandel RJ, Manfredsson FP, Foust KD, Rising A, Reimsnider S, Nash K, Burger C. Mandel RJ, et al. Mol Ther. 2006 Mar;13(3):463-83. doi: 10.1016/j.ymthe.2005.11.009. Epub 2006 Jan 18. Mol Ther. 2006. PMID: 16412695 Free article. Review.

10

Time course of transgene expression after intrastriatal pseudotyped rAAV2/1, rAAV2/2, rAAV2/5, and rAAV2/8 transduction in the rat.

Reimsnider S, Manfredsson FP, Muzyczka N, Mandel RJ. Reimsnider S, et al. Among authors: mandel rj. Mol Ther. 2007 Aug;15(8):1504-11. doi: 10.1038/sj.mt.6300227. Epub 2007 Jun 12. Mol Ther. 2007. PMID: 17565350 Free article.

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