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Failures in clinical treatment of Staphylococcus aureus Infection with daptomycin are associated with alterations in surface charge, membrane phospholipid asymmetry, and drug binding.
Jones T, Yeaman MR, Sakoulas G, Yang SJ, Proctor RA, Sahl HG, Schrenzel J, Xiong YQ, Bayer AS. Jones T, et al. Among authors: sahl hg. Antimicrob Agents Chemother. 2008 Jan;52(1):269-78. doi: 10.1128/AAC.00719-07. Epub 2007 Oct 22. Antimicrob Agents Chemother. 2008. PMID: 17954690 Free PMC article.
Human beta-defensin 3 inhibits cell wall biosynthesis in Staphylococci.
Sass V, Schneider T, Wilmes M, Körner C, Tossi A, Novikova N, Shamova O, Sahl HG. Sass V, et al. Among authors: sahl hg. Infect Immun. 2010 Jun;78(6):2793-800. doi: 10.1128/IAI.00688-09. Epub 2010 Apr 12. Infect Immun. 2010. PMID: 20385753 Free PMC article.
Plectasin, a fungal defensin, targets the bacterial cell wall precursor Lipid II.
Schneider T, Kruse T, Wimmer R, Wiedemann I, Sass V, Pag U, Jansen A, Nielsen AK, Mygind PH, Raventós DS, Neve S, Ravn B, Bonvin AM, De Maria L, Andersen AS, Gammelgaard LK, Sahl HG, Kristensen HH. Schneider T, et al. Among authors: sahl hg. Science. 2010 May 28;328(5982):1168-72. doi: 10.1126/science.1185723. Science. 2010. PMID: 20508130
Immunity to lantibiotics.
Saris PE, Immonen T, Reis M, Sahl HG. Saris PE, et al. Among authors: sahl hg. Antonie Van Leeuwenhoek. 1996 Feb;69(2):151-9. doi: 10.1007/BF00399420. Antonie Van Leeuwenhoek. 1996. PMID: 8775975 Review.
211 results