Donehower LA - Search Results

1

20 years studying p53 functions in genetically engineered mice.

Donehower LA, Lozano G. Donehower LA, et al. Nat Rev Cancer. 2009 Nov;9(11):831-41. doi: 10.1038/nrc2731. Epub 2009 Sep 24. Nat Rev Cancer. 2009. PMID: 19776746 Review.

2

Activities of wildtype and mutant p53 in suppression of homologous recombination as measured by a retroviral vector system.

Lu X, Lozano G, Donehower LA. Lu X, et al. Among authors: donehower la. Mutat Res. 2003 Jan 28;522(1-2):69-83. doi: 10.1016/s0027-5107(02)00261-0. Mutat Res. 2003. PMID: 12517413

3

Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models.

Terzian T, Dumble M, Arbab F, Thaller C, Donehower LA, Lozano G, Justice MJ, Roop DR, Box NF. Terzian T, et al. Among authors: donehower la. J Pathol. 2011 Aug;224(4):540-52. doi: 10.1002/path.2891. Epub 2011 Jun 14. J Pathol. 2011. PMID: 21674502 Free PMC article.

4

Pla2g16 phospholipase mediates gain-of-function activities of mutant p53.

Xiong S, Tu H, Kollareddy M, Pant V, Li Q, Zhang Y, Jackson JG, Suh YA, Elizondo-Fraire AC, Yang P, Chau G, Tashakori M, Wasylishen AR, Ju Z, Solomon H, Rotter V, Liu B, El-Naggar AK, Donehower LA, Martinez LA, Lozano G. Xiong S, et al. Among authors: donehower la. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11145-50. doi: 10.1073/pnas.1404139111. Epub 2014 Jul 14. Proc Natl Acad Sci U S A. 2014. PMID: 25024203 Free PMC article.

5

p53 mutant mice that display early ageing-associated phenotypes.

Tyner SD, Venkatachalam S, Choi J, Jones S, Ghebranious N, Igelmann H, Lu X, Soron G, Cooper B, Brayton C, Park SH, Thompson T, Karsenty G, Bradley A, Donehower LA. Tyner SD, et al. Among authors: donehower la. Nature. 2002 Jan 3;415(6867):45-53. doi: 10.1038/415045a. Nature. 2002. PMID: 11780111

6

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours.

Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery CA Jr, Butel JS, Bradley A. Donehower LA, et al. Nature. 1992 Mar 19;356(6366):215-21. doi: 10.1038/356215a0. Nature. 1992. PMID: 1552940

7

Using mice to examine p53 functions in cancer, aging, and longevity.

Donehower LA. Donehower LA. Cold Spring Harb Perspect Biol. 2009 Dec;1(6):a001081. doi: 10.1101/cshperspect.a001081. Epub 2009 Nov 4. Cold Spring Harb Perspect Biol. 2009. PMID: 20457560 Free PMC article. Review.

8

Insights into wild-type and mutant p53 functions provided by genetically engineered mice.

Donehower LA. Donehower LA. Hum Mutat. 2014 Jun;35(6):715-27. doi: 10.1002/humu.22507. Epub 2014 Feb 5. Hum Mutat. 2014. PMID: 24415648

9

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53.

Jones SN, Roe AE, Donehower LA, Bradley A. Jones SN, et al. Among authors: donehower la. Nature. 1995 Nov 9;378(6553):206-8. doi: 10.1038/378206a0. Nature. 1995. PMID: 7477327

10

A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice.

Harvey M, Vogel H, Morris D, Bradley A, Bernstein A, Donehower LA. Harvey M, et al. Among authors: donehower la. Nat Genet. 1995 Mar;9(3):305-11. doi: 10.1038/ng0395-305. Nat Genet. 1995. PMID: 7773294

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