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Sulfamides as novel histone deacetylase inhibitors.
Wahhab A, Smil D, Ajamian A, Allan M, Chantigny Y, Therrien E, Nguyen N, Manku S, Leit S, Rahil J, Petschner AJ, Lu AH, Nicolescu A, Lefebvre S, Montcalm S, Fournel M, Yan TP, Li Z, Besterman JM, Déziel R. Wahhab A, et al. Among authors: manku s. Bioorg Med Chem Lett. 2009 Jan 15;19(2):336-40. doi: 10.1016/j.bmcl.2008.11.081. Epub 2008 Nov 27. Bioorg Med Chem Lett. 2009. PMID: 19084395
Novel HDAC6 isoform selective chiral small molecule histone deacetylase inhibitors.
Smil DV, Manku S, Chantigny YA, Leit S, Wahhab A, Yan TP, Fournel M, Maroun C, Li Z, Lemieux AM, Nicolescu A, Rahil J, Lefebvre S, Panetta A, Besterman JM, Déziel R. Smil DV, et al. Among authors: manku s. Bioorg Med Chem Lett. 2009 Feb 1;19(3):688-92. doi: 10.1016/j.bmcl.2008.12.045. Epub 2008 Dec 14. Bioorg Med Chem Lett. 2009. PMID: 19111466
N-Benzyl-1-heteroaryl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamides as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1).
Allan M, Manku S, Therrien E, Nguyen N, Styhler S, Robert MF, Goulet AC, Petschner AJ, Rahil G, Robert Macleod A, Déziel R, Besterman JM, Nguyen H, Wahhab A. Allan M, et al. Among authors: manku s. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1218-23. doi: 10.1016/j.bmcl.2008.12.075. Epub 2008 Dec 24. Bioorg Med Chem Lett. 2009. PMID: 19131248
Synthesis and evaluation of lysine derived sulfamides as histone deacetylase inhibitors.
Manku S, Allan M, Nguyen N, Ajamian A, Rodrigue J, Therrien E, Wang J, Guo T, Rahil J, Petschner AJ, Nicolescu A, Lefebvre S, Li Z, Fournel M, Besterman JM, Déziel R, Wahhab A. Manku S, et al. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1866-70. doi: 10.1016/j.bmcl.2009.02.075. Epub 2009 Feb 23. Bioorg Med Chem Lett. 2009. PMID: 19272776
23 results