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Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens.
Jiménez de Oya N, De Giovanni M, Fioravanti J, Übelhart R, Di Lucia P, Fiocchi A, Iacovelli S, Efremov DG, Caligaris-Cappio F, Jumaa H, Ghia P, Guidotti LG, Iannacone M. Jiménez de Oya N, et al. Among authors: iacovelli s. EMBO Mol Med. 2017 Nov;9(11):1482-1490. doi: 10.15252/emmm.201707732. EMBO Mol Med. 2017. PMID: 28899929 Free PMC article.
Identification of an aberrantly spliced form of HDMX in human tumors: a new mechanism for HDM2 stabilization.
Giglio S, Mancini F, Gentiletti F, Sparaco G, Felicioni L, Barassi F, Martella C, Prodosmo A, Iacovelli S, Buttitta F, Farsetti A, Soddu S, Marchetti A, Sacchi A, Pontecorvi A, Moretti F. Giglio S, et al. Among authors: iacovelli s. Cancer Res. 2005 Nov 1;65(21):9687-94. doi: 10.1158/0008-5472.CAN-05-0450. Cancer Res. 2005. PMID: 16266988 Free article.
Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis.
Cecchinelli B, Lavra L, Rinaldo C, Iacovelli S, Gurtner A, Gasbarri A, Ulivieri A, Del Prete F, Trovato M, Piaggio G, Bartolazzi A, Soddu S, Sciacchitano S. Cecchinelli B, et al. Among authors: iacovelli s. Mol Cell Biol. 2006 Jun;26(12):4746-57. doi: 10.1128/MCB.00959-05. Mol Cell Biol. 2006. PMID: 16738336 Free PMC article.
Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL.
Iacovelli S, Hug E, Bennardo S, Duehren-von Minden M, Gobessi S, Rinaldi A, Suljagic M, Bilbao D, Bolasco G, Eckl-Dorna J, Niederberger V, Autore F, Sica S, Laurenti L, Wang H, Cornall RJ, Clarke SH, Croce CM, Bertoni F, Jumaa H, Efremov DG. Iacovelli S, et al. Blood. 2015 Mar 5;125(10):1578-88. doi: 10.1182/blood-2014-07-587790. Epub 2015 Jan 6. Blood. 2015. PMID: 25564405 Free PMC article.
22 results