Glen AT - Search Results

1

Non-steroidal antiandrogens. Design of novel compounds based on an infrared study of the dominant conformation and hydrogen-bonding properties of a series of anilide antiandrogens.

Morris JJ, Hughes LR, Glen AT, Taylor PJ. Morris JJ, et al. Among authors: glen at. J Med Chem. 1991 Jan;34(1):447-55. doi: 10.1021/jm00105a067. J Med Chem. 1991. PMID: 1992146

2

Receptor binding and biological activity of steroidal and nonsteroidal antiandrogens.

Wakeling AE, Furr BJ, Glen AT, Hughes LR. Wakeling AE, et al. Among authors: glen at. J Steroid Biochem. 1981 Dec;15:355-9. doi: 10.1016/0022-4731(81)90297-1. J Steroid Biochem. 1981. PMID: 7339263 No abstract available.

3

N-(1-methyl-5-indolyl)-N'-(3-pyridyl)urea hydrochloride: the first selective 5-HT1C receptor antagonist.

Forbes IT, Kennett GA, Gadre A, Ham P, Hayward CJ, Martin RT, Thompson M, Wood MD, Baxter GS, Glen A, et al. Forbes IT, et al. J Med Chem. 1993 Apr 16;36(8):1104-7. doi: 10.1021/jm00060a019. J Med Chem. 1993. PMID: 8478907 No abstract available.

4

5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo[2,3-f]indole: a novel 5-HT2C/5-HT2B receptor antagonist with improved affinity, selectivity, and oral activity.

Forbes IT, Ham P, Booth DH, Martin RT, Thompson M, Baxter GS, Blackburn TP, Glen A, Kennett GA, Wood MD. Forbes IT, et al. J Med Chem. 1995 Jul 7;38(14):2524-30. doi: 10.1021/jm00014a004. J Med Chem. 1995. PMID: 7629791

5

A solid-phase approach towards the synthesis of PDE5 inhibitors.

Beer D, Bhalay G, Dunstan A, Glen A, Haberthuer S, Moser H. Beer D, et al. Bioorg Med Chem Lett. 2002 Aug 5;12(15):1973-6. doi: 10.1016/s0960-894x(02)00296-2. Bioorg Med Chem Lett. 2002. PMID: 12113821

6

The regioselective tert-butyldimethylsilylation of the 6'-hydroxyl group of lactose derivatives via their dibutylstannylene acetals.

Glen A, Leigh DA, Martin RP, Smart JP, Truscello AM. Glen A, et al. Carbohydr Res. 1993 Oct 4;248:365-9. doi: 10.1016/0008-6215(93)84143-t. Carbohydr Res. 1993. PMID: 8252543 No abstract available.

7

Design and synthesis of a library of chemokine antagonists.

Bhalay G, Albrecht B, Akhlaq M, Baettig U, Beer D, Brown Z, Charlton S, Dunstan A, Bradley M, Gedeck P, Glen A, Howe T, Keller T, Leighton-Davies J, Li A, McCarthy C, Mocquet C, Owen C, Nicklin P, Rosethorne E. Bhalay G, et al. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6249-52. doi: 10.1016/j.bmcl.2011.09.013. Epub 2011 Sep 10. Bioorg Med Chem Lett. 2011. PMID: 21940167

8

Potent and selective xanthine-based inhibitors of phosphodiesterase 5.

Arnold NJ, Arnold R, Beer D, Bhalay G, Collingwood SP, Craig S, Devereux N, Dodds M, Dunstan AR, Fairhurst RA, Farr D, Fullerton JD, Glen A, Gomez S, Haberthuer S, Hatto JD, Howes C, Jones D, Keller TH, Leuenberger B, Moser HE, Muller I, Naef R, Nicklin PA, Sandham DA, Turner KL, Tweed MF, Watson SJ, Zurini M. Arnold NJ, et al. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2376-9. doi: 10.1016/j.bmcl.2006.11.019. Epub 2006 Nov 10. Bioorg Med Chem Lett. 2007. PMID: 17337182

9

In vivo properties of SB 200646A, a 5-HT2C/2B receptor antagonist.

Kennett GA, Wood MD, Glen A, Grewal S, Forbes I, Gadre A, Blackburn TP. Kennett GA, et al. Br J Pharmacol. 1994 Mar;111(3):797-802. doi: 10.1111/j.1476-5381.1994.tb14808.x. Br J Pharmacol. 1994. PMID: 7912626 Free PMC article.

10

An investigation of the mechanism responsible for fluoxetine-induced hypophagia in rats.

Lightowler S, Wood M, Brown T, Glen A, Blackburn T, Tulloch I, Kennett G. Lightowler S, et al. Eur J Pharmacol. 1996 Jan 25;296(2):137-43. doi: 10.1016/0014-2999(95)00704-0. Eur J Pharmacol. 1996. PMID: 8838449

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