Huang P - Search Results

1

Small mitochondria-targeting molecules as anti-cancer agents.

Wang F, Ogasawara MA, Huang P. Wang F, et al. Among authors: huang p. Mol Aspects Med. 2010 Feb;31(1):75-92. doi: 10.1016/j.mam.2009.12.003. Epub 2009 Dec 6. Mol Aspects Med. 2010. PMID: 19995573 Free PMC article. Review.

2

Mitochondrial defects in cancer.

Carew JS, Huang P. Carew JS, et al. Among authors: huang p. Mol Cancer. 2002 Dec 9;1:9. doi: 10.1186/1476-4598-1-9. Mol Cancer. 2002. PMID: 12513701 Free PMC article. Review.

3

Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism.

Pelicano H, Feng L, Zhou Y, Carew JS, Hileman EO, Plunkett W, Keating MJ, Huang P. Pelicano H, et al. Among authors: huang p. J Biol Chem. 2003 Sep 26;278(39):37832-9. doi: 10.1074/jbc.M301546200. Epub 2003 Jul 9. J Biol Chem. 2003. PMID: 12853461 Free article.

4

Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications.

Carew JS, Zhou Y, Albitar M, Carew JD, Keating MJ, Huang P. Carew JS, et al. Among authors: huang p. Leukemia. 2003 Aug;17(8):1437-47. doi: 10.1038/sj.leu.2403043. Leukemia. 2003. PMID: 12886229

5

ROS stress in cancer cells and therapeutic implications.

Pelicano H, Carney D, Huang P. Pelicano H, et al. Among authors: huang p. Drug Resist Updat. 2004 Apr;7(2):97-110. doi: 10.1016/j.drup.2004.01.004. Drug Resist Updat. 2004. PMID: 15158766 Review.

6

Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia.

Xu RH, Pelicano H, Zhou Y, Carew JS, Feng L, Bhalla KN, Keating MJ, Huang P. Xu RH, et al. Among authors: huang p. Cancer Res. 2005 Jan 15;65(2):613-21. Cancer Res. 2005. PMID: 15695406

7

Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma.

Achanta G, Sasaki R, Feng L, Carew JS, Lu W, Pelicano H, Keating MJ, Huang P. Achanta G, et al. Among authors: huang p. EMBO J. 2005 Oct 5;24(19):3482-92. doi: 10.1038/sj.emboj.7600819. Epub 2005 Sep 15. EMBO J. 2005. PMID: 16163384 Free PMC article.

8

A novel mechanism of action of methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate: direct permeabilization of the inner mitochondrial membrane to inhibit electron transport and induce apoptosis.

Samudio I, Konopleva M, Pelicano H, Huang P, Frolova O, Bornmann W, Ying Y, Evans R, Contractor R, Andreeff M. Samudio I, et al. Among authors: huang p. Mol Pharmacol. 2006 Apr;69(4):1182-93. doi: 10.1124/mol.105.018051. Epub 2006 Jan 12. Mol Pharmacol. 2006. PMID: 16410408

9

A boronic-chalcone derivative exhibits potent anticancer activity through inhibition of the proteasome.

Achanta G, Modzelewska A, Feng L, Khan SR, Huang P. Achanta G, et al. Among authors: huang p. Mol Pharmacol. 2006 Jul;70(1):426-33. doi: 10.1124/mol.105.021311. Epub 2006 Apr 24. Mol Pharmacol. 2006. PMID: 16636137

10

Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism.

Pelicano H, Xu RH, Du M, Feng L, Sasaki R, Carew JS, Hu Y, Ramdas L, Hu L, Keating MJ, Zhang W, Plunkett W, Huang P. Pelicano H, et al. Among authors: huang p. J Cell Biol. 2006 Dec 18;175(6):913-23. doi: 10.1083/jcb.200512100. Epub 2006 Dec 11. J Cell Biol. 2006. PMID: 17158952 Free PMC article.

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