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The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.
Jinwal UK, Koren J 3rd, Borysov SI, Schmid AB, Abisambra JF, Blair LJ, Johnson AG, Jones JR, Shults CL, O'Leary JC 3rd, Jin Y, Buchner J, Cox MB, Dickey CA. Jinwal UK, et al. Among authors: cox mb. J Neurosci. 2010 Jan 13;30(2):591-9. doi: 10.1523/JNEUROSCI.4815-09.2010. J Neurosci. 2010. PMID: 20071522 Free PMC article.
FKBP51 and FKBP52 in signaling and disease.
Storer CL, Dickey CA, Galigniana MD, Rein T, Cox MB. Storer CL, et al. Among authors: cox mb. Trends Endocrinol Metab. 2011 Dec;22(12):481-90. doi: 10.1016/j.tem.2011.08.001. Epub 2011 Aug 31. Trends Endocrinol Metab. 2011. PMID: 21889356 Free PMC article. Review.
A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51.
O'Leary JC 3rd, Dharia S, Blair LJ, Brady S, Johnson AG, Peters M, Cheung-Flynn J, Cox MB, de Erausquin G, Weeber EJ, Jinwal UK, Dickey CA. O'Leary JC 3rd, et al. Among authors: cox mb. PLoS One. 2011;6(9):e24840. doi: 10.1371/journal.pone.0024840. Epub 2011 Sep 15. PLoS One. 2011. PMID: 21935478 Free PMC article.
The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop.
Schmid AB, Lagleder S, Gräwert MA, Röhl A, Hagn F, Wandinger SK, Cox MB, Demmer O, Richter K, Groll M, Kessler H, Buchner J. Schmid AB, et al. Among authors: cox mb. EMBO J. 2012 Mar 21;31(6):1506-17. doi: 10.1038/emboj.2011.472. Epub 2012 Jan 6. EMBO J. 2012. PMID: 22227520 Free PMC article.
The cochaperone SGTA (small glutamine-rich tetratricopeptide repeat-containing protein alpha) demonstrates regulatory specificity for the androgen, glucocorticoid, and progesterone receptors.
Paul A, Garcia YA, Zierer B, Patwardhan C, Gutierrez O, Hildenbrand Z, Harris DC, Balsiger HA, Sivils JC, Johnson JL, Buchner J, Chadli A, Cox MB. Paul A, et al. Among authors: cox mb. J Biol Chem. 2014 May 30;289(22):15297-308. doi: 10.1074/jbc.M113.535229. Epub 2014 Apr 21. J Biol Chem. 2014. PMID: 24753260 Free PMC article.
Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone.
Singh JK, Hutt DM, Tait B, Guy NC, Sivils JC, Ortiz NR, Payan AN, Komaragiri SK, Owens JJ, Culbertson D, Blair LJ, Dickey C, Kuo SY, Finley D, Dyson HJ, Cox MB, Chaudhary J, Gestwicki JE, Balch WE. Singh JK, et al. Among authors: cox mb. Cell Chem Biol. 2020 Mar 19;27(3):292-305.e6. doi: 10.1016/j.chembiol.2020.01.008. Epub 2020 Feb 3. Cell Chem Biol. 2020. PMID: 32017918 Free PMC article.
Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer.
Rodina A, Taldone T, Kang Y, Patel PD, Koren J 3rd, Yan P, DaGama Gomes EM, Yang C, Patel MR, Shrestha L, Ochiana SO, Santarossa C, Maharaj R, Gozman A, Cox MB, Erdjument-Bromage H, Hendrickson RC, Cerchietti L, Melnick A, Guzman ML, Chiosis G. Rodina A, et al. Among authors: cox mb. ACS Chem Biol. 2014 Aug 15;9(8):1698-705. doi: 10.1021/cb500256u. Epub 2014 Jun 17. ACS Chem Biol. 2014. PMID: 24934503 Free PMC article.
90 results