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Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and relapse after stem cell transplantation.
Micklethwaite KP, Savoldo B, Hanley PJ, Leen AM, Demmler-Harrison GJ, Cooper LJ, Liu H, Gee AP, Shpall EJ, Rooney CM, Heslop HE, Brenner MK, Bollard CM, Dotti G. Micklethwaite KP, et al. Blood. 2010 Apr 1;115(13):2695-703. doi: 10.1182/blood-2009-09-242263. Epub 2010 Jan 28. Blood. 2010. PMID: 20110422 Free PMC article.
Ex vivo expansion and prophylactic infusion of CMV-pp65 peptide-specific cytotoxic T-lymphocytes following allogeneic hematopoietic stem cell transplantation.
Micklethwaite K, Hansen A, Foster A, Snape E, Antonenas V, Sartor M, Shaw P, Bradstock K, Gottlieb D. Micklethwaite K, et al. Biol Blood Marrow Transplant. 2007 Jun;13(6):707-14. doi: 10.1016/j.bbmt.2007.02.004. Epub 2007 Apr 6. Biol Blood Marrow Transplant. 2007. PMID: 17531781 Free article. Clinical Trial.
Prophylactic infusion of cytomegalovirus-specific cytotoxic T lymphocytes stimulated with Ad5f35pp65 gene-modified dendritic cells after allogeneic hemopoietic stem cell transplantation.
Micklethwaite KP, Clancy L, Sandher U, Hansen AM, Blyth E, Antonenas V, Sartor MM, Bradstock KF, Gottlieb DJ. Micklethwaite KP, et al. Blood. 2008 Nov 15;112(10):3974-81. doi: 10.1182/blood-2008-06-161695. Epub 2008 Sep 3. Blood. 2008. PMID: 18768783 Free article. Clinical Trial.
Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study.
Cruz CR, Micklethwaite KP, Savoldo B, Ramos CA, Lam S, Ku S, Diouf O, Liu E, Barrett AJ, Ito S, Shpall EJ, Krance RA, Kamble RT, Carrum G, Hosing CM, Gee AP, Mei Z, Grilley BJ, Heslop HE, Rooney CM, Brenner MK, Bollard CM, Dotti G. Cruz CR, et al. Among authors: micklethwaite kp. Blood. 2013 Oct 24;122(17):2965-73. doi: 10.1182/blood-2013-06-506741. Epub 2013 Sep 12. Blood. 2013. PMID: 24030379 Free PMC article. Clinical Trial.
Addition of varicella zoster virus-specific T cells to cytomegalovirus, Epstein-Barr virus and adenovirus tri-specific T cells as adoptive immunotherapy in patients undergoing allogeneic hematopoietic stem cell transplantation.
Ma CK, Blyth E, Clancy L, Simms R, Burgess J, Brown R, Deo S, Micklethwaite KP, Gottlieb DJ. Ma CK, et al. Among authors: micklethwaite kp. Cytotherapy. 2015 Oct;17(10):1406-20. doi: 10.1016/j.jcyt.2015.07.005. Cytotherapy. 2015. PMID: 26349000 Clinical Trial.
Adjuvant Peptide Pulsed Dendritic Cell Vaccination in Addition to T Cell Adoptive Immunotherapy for Cytomegalovirus Infection in Allogeneic Hematopoietic Stem Cell Transplantation Recipients.
Ma CKK, Clancy L, Simms R, Burgess J, Deo S, Blyth E, Micklethwaite KP, Gottlieb DJ. Ma CKK, et al. Among authors: micklethwaite kp. Biol Blood Marrow Transplant. 2018 Jan;24(1):71-77. doi: 10.1016/j.bbmt.2017.08.028. Epub 2017 Aug 31. Biol Blood Marrow Transplant. 2018. PMID: 28864137 Free article.
Investigation of product-derived lymphoma following infusion of piggyBac-modified CD19 chimeric antigen receptor T cells.
Micklethwaite KP, Gowrishankar K, Gloss BS, Li Z, Street JA, Moezzi L, Mach MA, Sutrave G, Clancy LE, Bishop DC, Louie RHY, Cai C, Foox J, MacKay M, Sedlazeck FJ, Blombery P, Mason CE, Luciani F, Gottlieb DJ, Blyth E. Micklethwaite KP, et al. Blood. 2021 Oct 21;138(16):1391-1405. doi: 10.1182/blood.2021010858. Blood. 2021. PMID: 33974080 Free PMC article. Clinical Trial.
Development of CAR T-cell lymphoma in 2 of 10 patients effectively treated with piggyBac-modified CD19 CAR T cells.
Bishop DC, Clancy LE, Simms R, Burgess J, Mathew G, Moezzi L, Street JA, Sutrave G, Atkins E, McGuire HM, Gloss BS, Lee K, Jiang W, Maddock K, McCaughan G, Avdic S, Antonenas V, O'Brien TA, Shaw PJ, Irving DO, Gottlieb DJ, Blyth E, Micklethwaite KP. Bishop DC, et al. Among authors: micklethwaite kp. Blood. 2021 Oct 21;138(16):1504-1509. doi: 10.1182/blood.2021010813. Blood. 2021. PMID: 34010392 Free article. Clinical Trial. No abstract available.
Third-party CMV- and EBV-specific T-cells for first viral reactivation after allogeneic stem cell transplant.
Jiang W, Clancy LE, Avdic S, Sutrave G, Street J, Simms R, McGuire HM, Patrick E, Chan AS, McCaughan G, Myers N, Micklethwaite KP, Antonenas V, Selim AG, Ritchie D, Bateman CM, Shaw PJ, Blyth E, Gottlieb DJ. Jiang W, et al. Among authors: micklethwaite kp. Blood Adv. 2022 Sep 13;6(17):4949-4966. doi: 10.1182/bloodadvances.2022007103. Blood Adv. 2022. PMID: 35819448 Free PMC article.
43 results