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First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G.
Li M, Shandilya SM, Carpenter MA, Rathore A, Brown WL, Perkins AL, Harki DA, Solberg J, Hook DJ, Pandey KK, Parniak MA, Johnson JR, Krogan NJ, Somasundaran M, Ali A, Schiffer CA, Harris RS. Li M, et al. Among authors: somasundaran m. ACS Chem Biol. 2012 Mar 16;7(3):506-17. doi: 10.1021/cb200440y. Epub 2012 Jan 17. ACS Chem Biol. 2012. PMID: 22181350 Free PMC article.
Mass spectrometry tools for analysis of intermolecular interactions.
Auclair JR, Somasundaran M, Green KM, Evans JE, Schiffer CA, Ringe D, Petsko GA, Agar JN. Auclair JR, et al. Among authors: somasundaran m. Methods Mol Biol. 2012;896:387-98. doi: 10.1007/978-1-4614-3704-8_26. Methods Mol Biol. 2012. PMID: 22821539 Free PMC article.
Crystal structure of the DNA cytosine deaminase APOBEC3F: the catalytically active and HIV-1 Vif-binding domain.
Bohn MF, Shandilya SM, Albin JS, Kouno T, Anderson BD, McDougle RM, Carpenter MA, Rathore A, Evans L, Davis AN, Zhang J, Lu Y, Somasundaran M, Matsuo H, Harris RS, Schiffer CA. Bohn MF, et al. Among authors: somasundaran m. Structure. 2013 Jun 4;21(6):1042-50. doi: 10.1016/j.str.2013.04.010. Epub 2013 May 16. Structure. 2013. PMID: 23685212 Free PMC article.
The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.
Bohn MF, Shandilya SMD, Silvas TV, Nalivaika EA, Kouno T, Kelch BA, Ryder SP, Kurt-Yilmaz N, Somasundaran M, Schiffer CA. Bohn MF, et al. Among authors: somasundaran m. Structure. 2015 May 5;23(5):903-911. doi: 10.1016/j.str.2015.03.016. Epub 2015 Apr 23. Structure. 2015. PMID: 25914058 Free PMC article.
Mutations in Influenza A Virus Neuraminidase and Hemagglutinin Confer Resistance against a Broadly Neutralizing Hemagglutinin Stem Antibody.
Prachanronarong KL, Canale AS, Liu P, Somasundaran M, Hou S, Poh YP, Han T, Zhu Q, Renzette N, Zeldovich KB, Kowalik TF, Kurt-Yilmaz N, Jensen JD, Bolon DNA, Marasco WA, Finberg RW, Schiffer CA, Wang JP. Prachanronarong KL, et al. Among authors: somasundaran m. J Virol. 2019 Jan 4;93(2):e01639-18. doi: 10.1128/JVI.01639-18. Print 2019 Jan 15. J Virol. 2019. PMID: 30381484 Free PMC article.
64 results