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Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice.
Barnes MJ, Aksoylar H, Krebs P, Bourdeau T, Arnold CN, Xia Y, Khovananth K, Engel I, Sovath S, Lampe K, Laws E, Saunders A, Butcher GW, Kronenberg M, Steinbrecher K, Hildeman D, Grimes HL, Beutler B, Hoebe K. Barnes MJ, et al. Among authors: xia y. J Immunol. 2010 Apr 1;184(7):3743-54. doi: 10.4049/jimmunol.0903164. Epub 2010 Feb 26. J Immunol. 2010. PMID: 20190135 Free PMC article.
Precis on forward genetics in mice.
Beutler B, Du X, Xia Y. Beutler B, et al. Among authors: xia y. Nat Immunol. 2007 Jul;8(7):659-64. doi: 10.1038/ni0707-659. Nat Immunol. 2007. PMID: 17579639 Review. No abstract available.
A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha.
Siggs OM, Berger M, Krebs P, Arnold CN, Eidenschenk C, Huber C, Pirie E, Smart NG, Khovananth K, Xia Y, McInerney G, Karlsson Hedestam GB, Nemazee D, Beutler B. Siggs OM, et al. Among authors: xia y. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3046-51. doi: 10.1073/pnas.0915098107. Epub 2010 Jan 28. Proc Natl Acad Sci U S A. 2010. PMID: 20133626 Free PMC article.
ZBTB1 is a determinant of lymphoid development.
Siggs OM, Li X, Xia Y, Beutler B. Siggs OM, et al. Among authors: xia y. J Exp Med. 2012 Jan 16;209(1):19-27. doi: 10.1084/jem.20112084. Epub 2011 Dec 26. J Exp Med. 2012. PMID: 22201126 Free PMC article.
A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity.
Arnold CN, Pirie E, Dosenovic P, McInerney GM, Xia Y, Wang N, Li X, Siggs OM, Karlsson Hedestam GB, Beutler B. Arnold CN, et al. Among authors: xia y. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12286-93. doi: 10.1073/pnas.1209134109. Epub 2012 Jul 3. Proc Natl Acad Sci U S A. 2012. PMID: 22761313 Free PMC article.
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