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TACC3-TSC2 maintains nuclear envelope structure and controls cell division.
Gómez-Baldó L, Schmidt S, Maxwell CA, Bonifaci N, Gabaldón T, Vidalain PO, Senapedis W, Kletke A, Rosing M, Barnekow A, Rottapel R, Capellá G, Vidal M, Astrinidis A, Piekorz RP, Pujana MA. Gómez-Baldó L, et al. Among authors: senapedis w. Cell Cycle. 2010 Mar 15;9(6):1143-55. doi: 10.4161/cc.9.6.11018. Epub 2010 Mar 15. Cell Cycle. 2010. PMID: 20237422
XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.
Kim J, McMillan E, Kim HS, Venkateswaran N, Makkar G, Rodriguez-Canales J, Villalobos P, Neggers JE, Mendiratta S, Wei S, Landesman Y, Senapedis W, Baloglu E, Chow CB, Frink RE, Gao B, Roth M, Minna JD, Daelemans D, Wistuba II, Posner BA, Scaglioni PP, White MA. Kim J, et al. Among authors: senapedis w. Nature. 2016 Oct 6;538(7623):114-117. doi: 10.1038/nature19771. Epub 2016 Sep 28. Nature. 2016. PMID: 27680702 Free PMC article.
Targeting Nuclear Exporter Protein XPO1/CRM1 in Gastric Cancer.
Sexton R, Mahdi Z, Chaudhury R, Beydoun R, Aboukameel A, Khan HY, Baloglu E, Senapedis W, Landesman Y, Tesfaye A, Kim S, Philip PA, Azmi AS. Sexton R, et al. Among authors: senapedis w. Int J Mol Sci. 2019 Sep 28;20(19):4826. doi: 10.3390/ijms20194826. Int J Mol Sci. 2019. PMID: 31569391 Free PMC article.
Therapeutic Potential of Targeting PAK Signaling.
Senapedis W, Crochiere M, Baloglu E, Landesman Y. Senapedis W, et al. Anticancer Agents Med Chem. 2016;16(1):75-88. doi: 10.2174/1871520615666150617111414. Anticancer Agents Med Chem. 2016. PMID: 26081410 Review.
49 results