Babu YS - Search Results

1

Potent orally bioavailable purine nucleoside phosphorylase inhibitor BCX-4208 induces apoptosis in B- and T-lymphocytes--a novel treatment approach for autoimmune diseases, organ transplantation and hematologic malignancies.

Bantia S, Parker C, Upshaw R, Cunningham A, Kotian P, Kilpatrick JM, Morris P, Chand P, Babu YS. Bantia S, et al. Among authors: babu ys. Int Immunopharmacol. 2010 Jul;10(7):784-90. doi: 10.1016/j.intimp.2010.04.009. Epub 2010 Apr 22. Int Immunopharmacol. 2010. PMID: 20399911

2

Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors.

Ealick SE, Babu YS, Bugg CE, Erion MD, Guida WC, Montgomery JA, Secrist JA 3rd. Ealick SE, et al. Among authors: babu ys. Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11540-4. doi: 10.1073/pnas.88.24.11540. Proc Natl Acad Sci U S A. 1991. PMID: 1763067 Free PMC article.

3

Crystallization and preliminary X-ray investigation of factor D of human complement.

Narayana SV, Kilpatrick JM, el-Kabbani O, Babu YS, Bugg CE, Volanakis JE, DeLucas LJ. Narayana SV, et al. Among authors: babu ys. J Mol Biol. 1991 May 5;219(1):1-3. doi: 10.1016/0022-2836(91)90851-v. J Mol Biol. 1991. PMID: 2023254

4

Structure-based design of inhibitors of purine nucleoside phosphorylase. 3. 9-Arylmethyl derivatives of 9-deazaguanine substituted on the methylene group.

Erion MD, Niwas S, Rose JD, Ananthan S, Allen M, Secrist JA 3rd, Babu YS, Bugg CE, Guida WC, Ealick SE, et al. Erion MD, et al. Among authors: babu ys. J Med Chem. 1993 Nov 26;36(24):3771-83. doi: 10.1021/jm00076a004. J Med Chem. 1993. PMID: 8254607

5

Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(arylmethyl) derivatives of 9-deazaguanine.

Montgomery JA, Niwas S, Rose JD, Secrist JA 3rd, Babu YS, Bugg CE, Erion MD, Guida WC, Ealick SE. Montgomery JA, et al. Among authors: babu ys. J Med Chem. 1993 Jan 8;36(1):55-69. doi: 10.1021/jm00053a008. J Med Chem. 1993. PMID: 8421291

6

Structure-based design of inhibitors of purine nucleoside phosphorylase. 2. 9-Alicyclic and 9-heteroalicyclic derivatives of 9-deazaguanine.

Secrist JA 3rd, Niwas S, Rose JD, Babu YS, Bugg CE, Erion MD, Guida WC, Ealick SE, Montgomery JA. Secrist JA 3rd, et al. Among authors: babu ys. J Med Chem. 1993 Jun 25;36(13):1847-54. doi: 10.1021/jm00065a007. J Med Chem. 1993. PMID: 8515423

7

Guanidinobenzoic acid inhibitors of influenza virus neuraminidase.

Sudbeck EA, Jedrzejas MJ, Singh S, Brouillette WJ, Air GM, Laver WG, Babu YS, Bantia S, Chand P, Chu N, Montgomery JA, Walsh DA, Luo M. Sudbeck EA, et al. Among authors: babu ys. J Mol Biol. 1997 Apr 4;267(3):584-94. doi: 10.1006/jmbi.1996.0885. J Mol Biol. 1997. PMID: 9126840

8

Design and synthesis of benzoic acid derivatives as influenza neuraminidase inhibitors using structure-based drug design.

Chand P, Babu YS, Bantia S, Chu N, Cole LB, Kotian PL, Laver WG, Montgomery JA, Pathak VP, Petty SL, Shrout DP, Walsh DA, Walsh GM. Chand P, et al. Among authors: babu ys. J Med Chem. 1997 Dec 5;40(25):4030-52. doi: 10.1021/jm970479e. J Med Chem. 1997. PMID: 9406595

9

Generation and characterization of a mutant of influenza A virus selected with the neuraminidase inhibitor BCX-140.

Bantia S, Ghate AA, Ananth SL, Babu YS, Air GM, Walsh GM. Bantia S, et al. Among authors: babu ys. Antimicrob Agents Chemother. 1998 Apr;42(4):801-7. doi: 10.1128/AAC.42.4.801. Antimicrob Agents Chemother. 1998. PMID: 9559786 Free PMC article.

10

Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity.

Jing H, Babu YS, Moore D, Kilpatrick JM, Liu XY, Volanakis JE, Narayana SV. Jing H, et al. Among authors: babu ys. J Mol Biol. 1998 Oct 9;282(5):1061-81. doi: 10.1006/jmbi.1998.2089. J Mol Biol. 1998. PMID: 9753554

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