Spenkelink B - Search Results

1

Stereoselective conjugation, transport and bioactivity of s- and R-hesperetin enantiomers in vitro.

Brand W, Shao J, Hoek-van den Hil EF, van Elk KN, Spenkelink B, de Haan LH, Rein MJ, Dionisi F, Williamson G, van Bladeren PJ, Rietjens IM. Brand W, et al. Among authors: spenkelink b. J Agric Food Chem. 2010 May 26;58(10):6119-25. doi: 10.1021/jf1008617. J Agric Food Chem. 2010. PMID: 20441166

2

Physiologically based biokinetic model of bioactivation and detoxification of the alkenylbenzene methyleugenol in rat.

Al-Subeihi AA, Spenkelink B, Rachmawati N, Boersma MG, Punt A, Vervoort J, van Bladeren PJ, Rietjens IM. Al-Subeihi AA, et al. Among authors: spenkelink b. Toxicol In Vitro. 2011 Feb;25(1):267-85. doi: 10.1016/j.tiv.2010.08.019. Epub 2010 Sep 7. Toxicol In Vitro. 2011. PMID: 20828604

3

Physiologically based kinetic modeling of bioactivation and detoxification of the alkenylbenzene methyleugenol in human as compared with rat.

Al-Subeihi AA, Spenkelink B, Punt A, Boersma MG, van Bladeren PJ, Rietjens IM. Al-Subeihi AA, et al. Among authors: spenkelink b. Toxicol Appl Pharmacol. 2012 May 1;260(3):271-84. doi: 10.1016/j.taap.2012.03.005. Epub 2012 Mar 14. Toxicol Appl Pharmacol. 2012. PMID: 22445790

4

Conversion of major soy isoflavone glucosides and aglycones in in vitro intestinal models.

Islam MA, Punt A, Spenkelink B, Murk AJ, Rolaf van Leeuwen FX, Rietjens IM. Islam MA, et al. Among authors: spenkelink b. Mol Nutr Food Res. 2014 Mar;58(3):503-15. doi: 10.1002/mnfr.201300390. Epub 2013 Nov 18. Mol Nutr Food Res. 2014. PMID: 24668774

5

Integrating in vitro data and physiologically based kinetic (PBK) modelling to assess the in vivo potential developmental toxicity of a series of phenols.

Strikwold M, Spenkelink B, de Haan LHJ, Woutersen RA, Punt A, Rietjens IMCM. Strikwold M, et al. Among authors: spenkelink b. Arch Toxicol. 2017 May;91(5):2119-2133. doi: 10.1007/s00204-016-1881-x. Epub 2016 Nov 4. Arch Toxicol. 2017. PMID: 27815601 Free PMC article.

6

Effects of Maerua subcordata (Gilg) DeWolf on electrophile-responsive element (EpRE)-mediated gene expression in vitro.

Gebrelibanos Hiben M, de Haan L, Spenkelink B, Wesseling S, Louisse J, Vervoort J, Rietjens IMCM. Gebrelibanos Hiben M, et al. Among authors: spenkelink b. PLoS One. 2019 Apr 15;14(4):e0215155. doi: 10.1371/journal.pone.0215155. eCollection 2019. PLoS One. 2019. PMID: 30986264 Free PMC article.

7

Use of Physiologically Based Pharmacokinetic Modeling to Predict Human Gut Microbial Conversion of Daidzein to S-Equol.

Wang Q, Spenkelink B, Boonpawa R, Rietjens IMCM. Wang Q, et al. Among authors: spenkelink b. J Agric Food Chem. 2022 Jan 12;70(1):343-352. doi: 10.1021/acs.jafc.1c03950. Epub 2021 Dec 2. J Agric Food Chem. 2022. PMID: 34855380 Free PMC article.

8

Quercetin increases the bioavailability of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rats.

Schutte ME, Alink GM, Freidig AP, Spenkelink B, Vaessen JC, van de Sandt JJ, Groten JP, Rietjens IM. Schutte ME, et al. Among authors: spenkelink b. Food Chem Toxicol. 2008 Nov;46(11):3422-8. doi: 10.1016/j.fct.2008.08.015. Epub 2008 Aug 22. Food Chem Toxicol. 2008. PMID: 18783729

9

In vivo validation of DNA adduct formation by estragole in rats predicted by physiologically based biodynamic modelling.

Paini A, Punt A, Scholz G, Gremaud E, Spenkelink B, Alink G, Schilter B, van Bladeren PJ, Rietjens IM. Paini A, et al. Among authors: spenkelink b. Mutagenesis. 2012 Nov;27(6):653-63. doi: 10.1093/mutage/ges031. Epub 2012 Jul 27. Mutagenesis. 2012. PMID: 22844077

10

Combining in vitro embryotoxicity data with physiologically based kinetic (PBK) modelling to define in vivo dose-response curves for developmental toxicity of phenol in rat and human.

Strikwold M, Spenkelink B, Woutersen RA, Rietjens IM, Punt A. Strikwold M, et al. Among authors: spenkelink b. Arch Toxicol. 2013 Sep;87(9):1709-23. doi: 10.1007/s00204-013-1107-4. Epub 2013 Aug 14. Arch Toxicol. 2013. PMID: 23943240

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