Coughlan K - Search Results

1

The involvement of sphingosine kinase 1 in LPS-induced Toll-like receptor 4-mediated accumulation of HIF-1α protein, activation of ASK1 and production of the pro-inflammatory cytokine IL-6.

Pchejetski D, Nunes J, Coughlan K, Lall H, Pitson SM, Waxman J, Sumbayev VV. Pchejetski D, et al. Among authors: coughlan k. Immunol Cell Biol. 2011 Feb;89(2):268-74. doi: 10.1038/icb.2010.91. Epub 2010 Jul 27. Immunol Cell Biol. 2011. PMID: 20661259

2

HIF-1alpha protein is an essential factor for protection of myeloid cells against LPS-induced depletion of ATP and apoptosis that supports Toll-like receptor 4-mediated production of IL-6.

Lall H, Coughlan K, Sumbayev VV. Lall H, et al. Among authors: coughlan k. Mol Immunol. 2008 Jun;45(11):3045-9. doi: 10.1016/j.molimm.2008.03.014. Epub 2008 May 6. Mol Immunol. 2008. PMID: 18462799

3

Apoptosis signal-regulating kinase 1 (ASK1) and HIF-1alpha protein are essential factors for nitric oxide-dependent accumulation of p53 in THP-1 human myeloid macrophages.

Jawahir M, Nicholas SA, Coughlan K, Sumbayev VV. Jawahir M, et al. Among authors: coughlan k. Apoptosis. 2008 Dec;13(12):1410-6. doi: 10.1007/s10495-008-0267-9. Apoptosis. 2008. PMID: 18841476

4

Dysfunctional mitochondria contain endogenous high-affinity human Toll-like receptor 4 (TLR4) ligands and induce TLR4-mediated inflammatory reactions.

Nicholas SA, Coughlan K, Yasinska I, Lall GS, Gibbs BF, Calzolai L, Sumbayev VV. Nicholas SA, et al. Among authors: coughlan k. Int J Biochem Cell Biol. 2011 Apr;43(4):674-81. doi: 10.1016/j.biocel.2011.01.012. Epub 2011 Jan 22. Int J Biochem Cell Biol. 2011. PMID: 21262374

5

Crucial involvement of xanthine oxidase in the intracellular signalling networks associated with human myeloid cell function.

Abooali M, Lall GS, Coughlan K, Lall HS, Gibbs BF, Sumbayev VV. Abooali M, et al. Among authors: coughlan k. Sci Rep. 2014 Sep 9;4:6307. doi: 10.1038/srep06307. Sci Rep. 2014. PMID: 25200751 Free PMC article.

6

Characterizing the mechanism of action for mRNA therapeutics for the treatment of propionic acidemia, methylmalonic acidemia, and phenylketonuria.

Baek R, Coughlan K, Jiang L, Liang M, Ci L, Singh H, Zhang H, Kaushal N, Rajlic IL, Van L, Dimen R, Cavedon A, Yin L, Rice L, Frassetto A, Guey L, Finn P, Martini PGV. Baek R, et al. Among authors: coughlan k. Nat Commun. 2024 May 7;15(1):3804. doi: 10.1038/s41467-024-47460-9. Nat Commun. 2024. PMID: 38714648 Free PMC article.

7

The Quality in Acute Stroke Care (QASC) global scale-up using a cascading facilitation framework: a qualitative process evaluation.

McInnes E, Dale S, Bagot K, Coughlan K, Grimshaw J, Pfeilschifter W, Cadilhac DA, Fischer T, van der Merwe J; QASC Europe Steering Committee; QASC Europe Implementation Committee; Middleton S. McInnes E, et al. Among authors: coughlan k. BMC Health Serv Res. 2024 Jan 29;24(1):144. doi: 10.1186/s12913-024-10617-9. BMC Health Serv Res. 2024. PMID: 38287332 Free PMC article.

8

Fever, Hyperglycemia, and Swallowing Management in Stroke Unit and Non-Stroke-Unit European Hospitals: A Quality in Acute Stroke Care (QASC) Europe Substudy.

Ding R, Betihavas V, McElduff B, Dale S, Coughlan K, McInnes E, Middleton S, Fasugba O; QASC Europe Investigators. Ding R, et al. Among authors: coughlan k. J Neurosci Nurs. 2024 Apr 1;56(2):42-48. doi: 10.1097/JNN.0000000000000743. Epub 2023 Dec 7. J Neurosci Nurs. 2024. PMID: 38064588

9

Repeat Sampling of Female Passerines During Reproduction Reveals Surprising Higher Plasma Oxidative Damage During Resting Compared to Active State.

Coughlan K, Sadowska ET, Bauchinger U. Coughlan K, et al. Integr Comp Biol. 2023 Dec 29;63(6):1197-1208. doi: 10.1093/icb/icad120. Integr Comp Biol. 2023. PMID: 37698890 Free PMC article.

10

How registry data are used to inform activities for stroke care quality improvement across 55 countries: A cross-sectional survey of Registry of Stroke Care Quality (RES-Q) hospitals.

Fasugba O, Sedani R, Mikulik R, Dale S, Vařecha M, Coughlan K, McElduff B, McInnes E, Hladíková S, Cadilhac DA, Middleton S. Fasugba O, et al. Among authors: coughlan k. Eur J Neurol. 2024 Jan;31(1):e16024. doi: 10.1111/ene.16024. Epub 2023 Aug 21. Eur J Neurol. 2024. PMID: 37540834 Free PMC article.

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