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3,339 results

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Page 1
Discovery of 2-aminoimidazopyridine adenosine A(2A) receptor antagonists.
McGuinness BF, Cole AG, Dong G, Brescia MR, Shao Y, Henderson I, Rokosz LL, Stauffer TM, Mannava N, Kimble EF, Hicks C, White N, Wines PG, Quadros E. McGuinness BF, et al. Among authors: white n. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6845-9. doi: 10.1016/j.bmcl.2010.08.064. Epub 2010 Aug 19. Bioorg Med Chem Lett. 2010. PMID: 20869242
Novel pyrrolidine ureas as C-C chemokine receptor 1 (CCR1) antagonists.
Merritt JR, Liu J, Quadros E, Morris ML, Liu R, Zhang R, Jacob B, Postelnek J, Hicks CM, Chen W, Kimble EF, Rogers WL, O'Brien L, White N, Desai H, Bansal S, King G, Ohlmeyer MJ, Appell KC, Webb ML. Merritt JR, et al. Among authors: white n. J Med Chem. 2009 Mar 12;52(5):1295-301. doi: 10.1021/jm801416q. J Med Chem. 2009. PMID: 19183043
Novel pyrrolidine heterocycles as CCR1 antagonists.
Merritt JR, James R, Paradkar VM, Zhang C, Liu R, Liu J, Jacob B, Chiriac C, Ohlmeyer MJ, Quadros E, Wines P, Postelnek J, Hicks CM, Chen W, Kimble EF, O'Brien L, White N, Desai H, Appell KC, Webb ML. Merritt JR, et al. Among authors: white n. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5477-9. doi: 10.1016/j.bmcl.2010.07.082. Epub 2010 Jul 24. Bioorg Med Chem Lett. 2010. PMID: 20708929
Potent and orally active non-peptide antagonists of the human melanocortin-4 receptor based on a series of trans-2-disubstituted cyclohexylpiperazines.
Tucci FC, White NS, Markison S, Joppa M, Tran JA, Fleck BA, Madan A, Dyck BP, Parker J, Pontillo J, Arellano LM, Marinkovic D, Jiang W, Chen CW, Gogas KR, Goodfellow VS, Saunders J, Foster AC, Chen C. Tucci FC, et al. Bioorg Med Chem Lett. 2005 Oct 1;15(19):4389-95. doi: 10.1016/j.bmcl.2005.06.071. Bioorg Med Chem Lett. 2005. PMID: 16098742
Arylpropionylpiperazines as antagonists of the human melanocortin-4 receptor.
Jiang W, Tucci FC, Chen CW, Arellano M, Tran JA, White NS, Marinkovic D, Pontillo J, Fleck BA, Wen J, Saunders J, Madan A, Foster AC, Chen C. Jiang W, et al. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4674-8. doi: 10.1016/j.bmcl.2006.05.088. Epub 2006 Jun 13. Bioorg Med Chem Lett. 2006. PMID: 16777413
Propionylpiperazines as human melanocortin-4 receptor ligands.
Chen CW, Tran JA, Jiang W, Tucci FC, Arellano M, Wen J, Fleck BA, Marinkovic D, White NS, Pontillo J, Saunders J, Madan A, Foster AC, Chen C. Chen CW, et al. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4800-3. doi: 10.1016/j.bmcl.2006.06.075. Epub 2006 Jul 7. Bioorg Med Chem Lett. 2006. PMID: 16824757
Structure based design of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors from a phenotypic screen.
Palacios DS, Meredith E, Kawanami T, Adams C, Chen X, Darsigny V, Geno E, Palermo M, Baird D, Boynton G, Busby SA, George EL, Guy C, Hewett J, Tierney L, Thigale S, Weihofen W, Wang L, White N, Yin M, Argikar UA. Palacios DS, et al. Among authors: white n. Bioorg Med Chem Lett. 2018 Feb 1;28(3):365-370. doi: 10.1016/j.bmcl.2017.12.037. Epub 2017 Dec 18. Bioorg Med Chem Lett. 2018. PMID: 29275937
3,339 results