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The reactions of oxicam and sulfoanilide non steroidal anti-inflammatory drugs with hypochlorous acid: determination of the rate constants with an assay based on the competition with para-aminobenzoic acid chlorination and identification of some oxidation products.
Van Antwerpen P, Dubois J, Gelbcke M, Neve J. Van Antwerpen P, et al. Among authors: gelbcke m. Free Radic Res. 2004 Mar;38(3):251-8. doi: 10.1080/10715760310001659404. Free Radic Res. 2004. PMID: 15129733
Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli.
Lamoral-Theys D, Pottier L, Kerff F, Dufrasne F, Proutière F, Wauthoz N, Neven P, Ingrassia L, Antwerpen PV, Lefranc F, Gelbcke M, Pirotte B, Kraus JL, Nève J, Kornienko A, Kiss R, Dubois J. Lamoral-Theys D, et al. Among authors: gelbcke m. Bioorg Med Chem. 2010 Jun 1;18(11):3823-33. doi: 10.1016/j.bmc.2010.04.047. Epub 2010 Apr 21. Bioorg Med Chem. 2010. PMID: 20466556 Free PMC article.
N-(2-{3-[3,5-bis(trifluoromethyl)phenyl]ureido}ethyl)-glycyrrhetinamide (6b): a novel anticancer glycyrrhetinic acid derivative that targets the proteasome and displays anti-kinase activity.
Lallemand B, Chaix F, Bury M, Bruyère C, Ghostin J, Becker JP, Delporte C, Gelbcke M, Mathieu V, Dubois J, Prévost M, Jabin I, Kiss R. Lallemand B, et al. Among authors: gelbcke m. J Med Chem. 2011 Oct 13;54(19):6501-13. doi: 10.1021/jm200285z. Epub 2011 Sep 2. J Med Chem. 2011. PMID: 21888390
DYRK1A kinase inhibitors with emphasis on cancer.
Ionescu A, Dufrasne F, Gelbcke M, Jabin I, Kiss R, Lamoral-Theys D. Ionescu A, et al. Among authors: gelbcke m. Mini Rev Med Chem. 2012 Nov;12(13):1315-29. doi: 10.2174/13895575112091315. Mini Rev Med Chem. 2012. PMID: 23016545 Review.
42 results