Atwal K - Search Results

1

Triphenylphosphine oxide is a potent and selective inhibitor of the transient receptor potential melastatin-5 ion channel.

Palmer RK, Atwal K, Bakaj I, Carlucci-Derbyshire S, Buber MT, Cerne R, Cortés RY, Devantier HR, Jorgensen V, Pawlyk A, Lee SP, Sprous DG, Zhang Z, Bryant R. Palmer RK, et al. Among authors: atwal k. Assay Drug Dev Technol. 2010 Dec;8(6):703-13. doi: 10.1089/adt.2010.0334. Assay Drug Dev Technol. 2010. PMID: 21158685

2

Dihydropyrimidine calcium channel blockers. 2. 3-substituted-4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines.

Atwal KS, Rovnyak GC, Kimball SD, Floyd DM, Moreland S, Swanson BN, Gougoutas JZ, Schwartz J, Smillie KM, Malley MF. Atwal KS, et al. J Med Chem. 1990 Sep;33(9):2629-35. doi: 10.1021/jm00171a044. J Med Chem. 1990. PMID: 2391701

3

Discovery of ((S)-5-(methoxymethyl)-7-(1-methyl-1H-indol-2-yl)-2-(trifluoromethyl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)((S)-2-(3-methylisoxazol-5-yl)pyrrolidin-1-yl)methanone as a potent and selective I(Kur) inhibitor.

Finlay HJ, Lloyd J, Vaccaro W, Kover A, Yan L, Bhave G, Prol J, Huynh T, Bhandaru R, Caringal Y, DiMarco J, Gan J, Harper T, Huang C, Conder ML, Sun H, Levesque P, Blanar M, Atwal K, Wexler R. Finlay HJ, et al. Among authors: atwal k. J Med Chem. 2012 Apr 12;55(7):3036-48. doi: 10.1021/jm201386u. Epub 2012 Mar 21. J Med Chem. 2012. PMID: 22409629

4

Dihydropyrimidine calcium channel blockers: 2-heterosubstituted 4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines.

Atwal KS, Rovnyak GC, Schwartz J, Moreland S, Hedberg A, Gougoutas JZ, Malley MF, Floyd DM. Atwal KS, et al. J Med Chem. 1990 May;33(5):1510-5. doi: 10.1021/jm00167a035. J Med Chem. 1990. PMID: 2329573

5

Tryptamine and homotryptamine-based sulfonamides as potent and selective inhibitors of 15-lipoxygenase.

Weinstein DS, Liu W, Gu Z, Langevine C, Ngu K, Fadnis L, Combs DW, Sitkoff D, Ahmad S, Zhuang S, Chen X, Wang FL, Loughney DA, Atwal KS, Zahler R, Macor JE, Madsen CS, Murugesan N. Weinstein DS, et al. Among authors: atwal ks. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1435-40. doi: 10.1016/j.bmcl.2004.12.081. Bioorg Med Chem Lett. 2005. PMID: 15713402

6

Substituted 1,2,3,4-tetrahydroaminonaphthols: antihypertensive agents, calcium channel blockers, and adrenergic receptor blockers with catecholamine-depleting effects.

Atwal KS, O'Reilly BC, Ruby EP, Turk CF, Aberg G, Asaad MM, Bergey JL, Moreland S, Powell JR. Atwal KS, et al. J Med Chem. 1987 Apr;30(4):627-35. doi: 10.1021/jm00387a008. J Med Chem. 1987. PMID: 2435902

7

Pyrano-[2,3b]-pyridines as potassium channel antagonists.

Finlay HJ, Lloyd J, Nyman M, Conder ML, West T, Levesque P, Atwal K. Finlay HJ, et al. Among authors: atwal k. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2714-8. doi: 10.1016/j.bmcl.2008.03.026. Epub 2008 Mar 14. Bioorg Med Chem Lett. 2008. PMID: 18374568

8

Dihydropyrazolopyrimidines containing benzimidazoles as K(V)1.5 potassium channel antagonists.

Lloyd J, Finlay HJ, Atwal K, Kover A, Prol J, Yan L, Bhandaru R, Vaccaro W, Huynh T, Huang CS, Conder M, Jenkins-West T, Sun H, Li D, Levesque P. Lloyd J, et al. Among authors: atwal k. Bioorg Med Chem Lett. 2009 Sep 15;19(18):5469-73. doi: 10.1016/j.bmcl.2009.07.083. Epub 2009 Jul 22. Bioorg Med Chem Lett. 2009. PMID: 19665893

9

Pyrrolidine amides of pyrazolodihydropyrimidines as potent and selective KV1.5 blockers.

Lloyd J, Finlay HJ, Vacarro W, Hyunh T, Kover A, Bhandaru R, Yan L, Atwal K, Conder ML, Jenkins-West T, Shi H, Huang C, Li D, Sun H, Levesque P. Lloyd J, et al. Among authors: atwal k. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1436-9. doi: 10.1016/j.bmcl.2009.12.085. Epub 2010 Jan 4. Bioorg Med Chem Lett. 2010. PMID: 20097068

10

Triazolo and imidazo dihydropyrazolopyrimidine potassium channel antagonists.

Finlay HJ, Jiang J, Caringal Y, Kover A, Conder ML, Xing D, Levesque P, Harper T, Hsueh MM, Atwal K, Blanar M, Wexler R, Lloyd J. Finlay HJ, et al. Among authors: atwal k. Bioorg Med Chem Lett. 2013 Mar 15;23(6):1743-7. doi: 10.1016/j.bmcl.2013.01.064. Epub 2013 Jan 26. Bioorg Med Chem Lett. 2013. PMID: 23414837

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