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Thymol and related alkyl phenols activate the hTRPA1 channel.
Lee SP, Buber MT, Yang Q, Cerne R, Cortés RY, Sprous DG, Bryant RW. Lee SP, et al. Among authors: cerne r. Br J Pharmacol. 2008 Apr;153(8):1739-49. doi: 10.1038/bjp.2008.85. Epub 2008 Mar 10. Br J Pharmacol. 2008. PMID: 18334983 Free PMC article.
Pharmacological characterization of the neurotrophic sesquiterpene jiadifenolide reveals a non-convulsant signature and potential for progression in neurodegenerative disease studies.
Witkin JM, Shenvi RA, Li X, Gleason SD, Weiss J, Morrow D, Catow JT, Wakulchik M, Ohtawa M, Lu HH, Martinez MD, Schkeryantz JM, Carpenter TS, Lightstone FC, Cerne R. Witkin JM, et al. Among authors: cerne r. Biochem Pharmacol. 2018 Sep;155:61-70. doi: 10.1016/j.bcp.2018.06.022. Epub 2018 Jun 22. Biochem Pharmacol. 2018. PMID: 29940173 Free PMC article.
Further evaluation of the potential anxiolytic activity of imidazo[1,5-a][1,4]diazepin agents selective for α2/3-containing GABAA receptors.
Witkin JM, Cerne R, Wakulchik M, S J, Gleason SD, Jones TM, Li G, Arnold LA, Li JX, Schkeryantz JM, Methuku KR, Cook JM, Poe MM. Witkin JM, et al. Among authors: cerne r. Pharmacol Biochem Behav. 2017 Jun;157:35-40. doi: 10.1016/j.pbb.2017.04.009. Epub 2017 Apr 22. Pharmacol Biochem Behav. 2017. PMID: 28442369 Free PMC article.
54 results