Koren AO - Search Results

1

Pharmacokinetic modeling and [¹²³]5-IA-85380 single photon emission computed tomography imaging in baboons: optimization of dosing regimen for ABT-089.

Chin CL, Carr RA, Llano DA, Barret O, Xu H, Batis J, Koren AO, Seibyl JP, Marsh KC, Tamagnan G, Decker MW, Day M, Fox GB. Chin CL, et al. Among authors: koren ao. J Pharmacol Exp Ther. 2011 Mar;336(3):716-23. doi: 10.1124/jpet.110.173609. Epub 2010 Dec 20. J Pharmacol Exp Ther. 2011. PMID: 21172907

2

Kinetic modeling and occupancy measures of the norepinephrine transporters in baboons using single photon emission computed tomography with (123)I-INER.

Tavares AA, Barret O, Batis J, Alagille D, Koren A, Papin C, Kudej G, Nice K, Kordower JH, Cosgrove KP, Kloczynski T, Brenner E, Seibyl J, Tamagnan G. Tavares AA, et al. Synapse. 2013 Jan;67(1):30-41. doi: 10.1002/syn.21613. Epub 2012 Oct 31. Synapse. 2013. PMID: 23042643

3

In vivo evaluation of [(123)I]MNI-420: a novel single photon emission computed tomography radiotracer for imaging of adenosine 2A receptors in brain.

Tavares AA, Batis J, Barret O, Alagille D, Vala C, Kudej G, Koren A, Cosgrove KP, Nice K, Kordower JH, Seibyl J, Tamagnan GD. Tavares AA, et al. Nucl Med Biol. 2013 Apr;40(3):403-9. doi: 10.1016/j.nucmedbio.2012.12.005. Epub 2013 Jan 16. Nucl Med Biol. 2013. PMID: 23332393

4

In vivo evaluation of [¹²³I]mZIENT as a SPECT radioligand for the serotonin transporter.

Batis J, Barret O, Alagille D, Koren AO, Stehouwer JS, Cosgrove K, Goodman M, Seibyl J, Tamagnan G. Batis J, et al. Among authors: koren ao. Nucl Med Biol. 2012 Nov;39(8):1137-41. doi: 10.1016/j.nucmedbio.2012.07.006. Nucl Med Biol. 2012. PMID: 23084043

5

Whole-body biodistribution, radiation absorbed dose, and brain SPET imaging with [123i]5-i-A-85380 in healthy human subjects.

Fujita M, Seibyl JP, Vaupel DB, Tamagnan G, Early M, Zoghbi SS, Baldwin RM, Horti AG, KoreN AO, Mukhin AG, Khan S, Bozkurt A, Kimes AS, London ED, Innis RB. Fujita M, et al. Among authors: koren ao. Eur J Nucl Med Mol Imaging. 2002 Feb;29(2):183-90. doi: 10.1007/s00259-001-0695-z. Eur J Nucl Med Mol Imaging. 2002. PMID: 11926380

6

Quantification of nicotinic acetylcholine receptors in human brain using [123I]5-I-A-85380 SPET.

Fujita M, Ichise M, van Dyck CH, Zoghbi SS, Tamagnan G, Mukhin AG, Bozkurt A, Seneca N, Tipre D, DeNucci CC, Iida H, Vaupel DB, Horti AG, Koren AO, Kimes AS, London ED, Seibyl JP, Baldwin RM, Innis RB. Fujita M, et al. Among authors: koren ao. Eur J Nucl Med Mol Imaging. 2003 Dec;30(12):1620-9. doi: 10.1007/s00259-003-1320-0. Epub 2003 Oct 2. Eur J Nucl Med Mol Imaging. 2003. PMID: 14523584 Clinical Trial.

7

Development of SPECT imaging agents for the norepinephrine transporters: [123I]INER.

Tamagnan GD, Brenner E, Alagille D, Staley JK, Haile C, Koren A, Early M, Baldwin RM, Tarazi FI, Baldessarini RJ, Jarkas N, Goodman MM, Seibyl JP. Tamagnan GD, et al. Bioorg Med Chem Lett. 2007 Jan 15;17(2):533-7. doi: 10.1016/j.bmcl.2006.10.018. Epub 2006 Oct 12. Bioorg Med Chem Lett. 2007. PMID: 17095215 Free PMC article.

8

Synthesis and receptor binding studies of halogenated N,N-dialkylel-(2-phenyl-1H-indol-3-yl)glyoxylamides to visualize peripheral benzodiazepine receptors with SPECT or PET.

Bennacef I, Haile CN, Schmidt A, Koren AO, Seibyl JP, Staley JK, Bois F, Baldwin RM, Tamagnan G. Bennacef I, et al. Among authors: koren ao. Bioorg Med Chem. 2006 Nov 15;14(22):7582-91. doi: 10.1016/j.bmc.2006.07.001. Bioorg Med Chem. 2006. PMID: 16908169

9

5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors.

Mukhin AG, Gündisch D, Horti AG, Koren AO, Tamagnan G, Kimes AS, Chambers J, Vaupel DB, King SL, Picciotto MR, Innis RB, London ED. Mukhin AG, et al. Among authors: koren ao. Mol Pharmacol. 2000 Mar;57(3):642-9. doi: 10.1124/mol.57.3.642. Mol Pharmacol. 2000. PMID: 10692507

10

Pharmacological and toxicological evaluation of 2-fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-F-A-85380), a ligand for imaging cerebral nicotinic acetylcholine receptors with positron emission tomography.

Vaupel DB, Tella SR, Huso DL, Wagner VO 3rd, Mukhin AG, Chefer SI, Horti AG, London ED, Koren AO, Kimes AS. Vaupel DB, et al. Among authors: koren ao. J Pharmacol Exp Ther. 2005 Jan;312(1):355-65. doi: 10.1124/jpet.104.073999. Epub 2004 Aug 26. J Pharmacol Exp Ther. 2005. PMID: 15331657

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