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Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts.
Kerkar SP, Muranski P, Kaiser A, Boni A, Sanchez-Perez L, Yu Z, Palmer DC, Reger RN, Borman ZA, Zhang L, Morgan RA, Gattinoni L, Rosenberg SA, Trinchieri G, Restifo NP. Kerkar SP, et al. Among authors: morgan ra. Cancer Res. 2010 Sep 1;70(17):6725-34. doi: 10.1158/0008-5472.CAN-10-0735. Epub 2010 Jul 20. Cancer Res. 2010. PMID: 20647327 Free PMC article.
Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy.
Hinrichs CS, Borman ZA, Gattinoni L, Yu Z, Burns WR, Huang J, Klebanoff CA, Johnson LA, Kerkar SP, Yang S, Muranski P, Palmer DC, Scott CD, Morgan RA, Robbins PF, Rosenberg SA, Restifo NP. Hinrichs CS, et al. Among authors: morgan ra. Blood. 2011 Jan 20;117(3):808-14. doi: 10.1182/blood-2010-05-286286. Epub 2010 Oct 22. Blood. 2011. PMID: 20971955 Free PMC article.
A TCR targeting the HLA-A*0201-restricted epitope of MAGE-A3 recognizes multiple epitopes of the MAGE-A antigen superfamily in several types of cancer.
Chinnasamy N, Wargo JA, Yu Z, Rao M, Frankel TL, Riley JP, Hong JJ, Parkhurst MR, Feldman SA, Schrump DS, Restifo NP, Robbins PF, Rosenberg SA, Morgan RA. Chinnasamy N, et al. Among authors: morgan ra. J Immunol. 2011 Jan 15;186(2):685-96. doi: 10.4049/jimmunol.1001775. Epub 2010 Dec 13. J Immunol. 2011. PMID: 21149604 Free PMC article.
Treating cancer with genetically engineered T cells.
Park TS, Rosenberg SA, Morgan RA. Park TS, et al. Among authors: morgan ra. Trends Biotechnol. 2011 Nov;29(11):550-7. doi: 10.1016/j.tibtech.2011.04.009. Epub 2011 Jun 12. Trends Biotechnol. 2011. PMID: 21663987 Free PMC article. Review.
344 results