Uskokovic MR - Search Results

1

A new insight into the role of rat cytochrome P450 24A1 in metabolism of selective analogs of 1α,25-dihydroxyvitamin D₃.

Rhieu SY, Annalora AJ, Gathungu RM, Vouros P, Uskokovic MR, Schuster I, Palmore GT, Reddy GS. Rhieu SY, et al. Among authors: uskokovic mr. Arch Biochem Biophys. 2011 May 1;509(1):33-43. doi: 10.1016/j.abb.2011.02.004. Epub 2011 Feb 19. Arch Biochem Biophys. 2011. PMID: 21338573 Free PMC article.

2

23-carboxy-24,25,26,27-tetranorvitamin D3 (calcioic acid) and 24-carboxy-25,26,27-trinorvitamin D3 (cholacalcioic acid): end products of 25-hydroxyvitamin D3 metabolism in rat kidney through C-24 oxidation pathway.

Reddy GS, Omdahl JL, Robinson M, Wang G, Palmore GT, Vicchio D, Yergey AL, Tserng KY, Uskokovic MR. Reddy GS, et al. Among authors: uskokovic mr. Arch Biochem Biophys. 2006 Nov 1;455(1):18-30. doi: 10.1016/j.abb.2006.08.021. Epub 2006 Sep 15. Arch Biochem Biophys. 2006. PMID: 17027908

3

Potent antiproliferative effects of 25-hydroxy-16-ene-23-yne-vitamin D₃ that resists the catalytic activity of both CYP27B1 and CYP24A1.

Rhieu SY, Annalora AJ, LaPorta E, Welsh J, Itoh T, Yamamoto K, Sakaki T, Chen TC, Uskokovic MR, Reddy GS. Rhieu SY, et al. Among authors: uskokovic mr. J Cell Biochem. 2014 Aug;115(8):1392-402. doi: 10.1002/jcb.24789. J Cell Biochem. 2014. PMID: 24535953

4

Metabolism of selective 20-epi-vitamin D₃ analogs in rat osteosarcoma UMR-106 cells: Isolation and identification of four novel C-1 fatty acid esters of 1α,25-dihydroxy-16-ene-20-epi-vitamin D₃.

Flarakos CC, Weiskopf A, Robinson M, Wang G, Vouros P, Sasso GJ, Uskokovic MR, Reddy GS. Flarakos CC, et al. Among authors: uskokovic mr. Steroids. 2017 Mar;119:18-30. doi: 10.1016/j.steroids.2016.12.013. Epub 2017 Jan 12. Steroids. 2017. PMID: 28089927

5

C-25 hydroxylation of 1alpha,24(R)-dihydroxyvitamin D3 is catalyzed by 25-hydroxyvitamin D3-24-hydroxylase (CYP24A1): metabolism studies with human keratinocytes and rat recombinant CYP24A1.

Astecker N, Bobrovnikova EA, Omdahl JL, Gennaro L, Vouros P, Schuster I, Uskokovic MR, Ishizuka S, Wang G, Reddy GS. Astecker N, et al. Among authors: uskokovic mr. Arch Biochem Biophys. 2004 Nov 15;431(2):261-70. doi: 10.1016/j.abb.2004.08.023. Arch Biochem Biophys. 2004. PMID: 15488475

6

Physiological significance of C-28 hydroxylation in the metabolism of 1alpha,25-dihydroxyvitamin D(2).

Rao DS, Siu-Caldera ML, Uskokovic MR, Horst RL, Reddy GS. Rao DS, et al. Among authors: uskokovic mr. Arch Biochem Biophys. 1999 Aug 15;368(2):319-28. doi: 10.1006/abbi.1999.1308. Arch Biochem Biophys. 1999. PMID: 10441383

7

1alpha,25-dihydroxy-16-ene-23-yne-vitamin D3 and 1alpha,25-dihydroxy-16-ene-23-yne-20-epi-vitamin D3: analogs of 1alpha,25-dihydroxyvitamin D3 that resist metabolism through the C-24 oxidation pathway are metabolized through the C-3 epimerization pathway.

Reddy GS, Rao DS, Siu-Caldera ML, Astecker N, Weiskopf A, Vouros P, Sasso GJ, Manchand PS, Uskokovic MR. Reddy GS, et al. Among authors: uskokovic mr. Arch Biochem Biophys. 2000 Nov 15;383(2):197-205. doi: 10.1006/abbi.2000.2074. Arch Biochem Biophys. 2000. PMID: 11185554

8

Production of 1alpha,25-dihydroxy-3-epi-vitamin D3 in two rat osteosarcoma cell lines (UMR 106 and ROS 17/2.8): existence of the C-3 epimerization pathway in ROS 17/2.8 cells in which the C-24 oxidation pathway is not expressed.

Siu-Caldera ML, Sekimoto H, Weiskopf A, Vouros P, Muralidharan KR, Okamura WH, Bishop J, Norman AW, Uskoković MR, Schuster I, Reddy GS. Siu-Caldera ML, et al. Among authors: uskokovic mr. Bone. 1999 May;24(5):457-63. doi: 10.1016/s8756-3282(99)00019-8. Bone. 1999. PMID: 10321905

9

Synthesis and anti-inflammatory properties of 1alpha,25-dihydroxy-16-ene-20-cyclopropyl-24-oxo-vitamin D3, a hypocalcemic, stable metabolite of 1alpha,25-dihydroxy-16-ene-20-cyclopropyl-vitamin D3.

Laverny G, Penna G, Uskokovic M, Marczak S, Maehr H, Jankowski P, Ceailles C, Vouros P, Smith B, Robinson M, Reddy GS, Adorini L. Laverny G, et al. J Med Chem. 2009 Apr 23;52(8):2204-13. doi: 10.1021/jm801365a. J Med Chem. 2009. PMID: 19309155

10

Isolation and identification of 1alpha-hydroxy-3-epi-vitamin D3, a potent suppressor of parathyroid hormone secretion.

Brown AJ, Ritter CS, Weiskopf AS, Vouros P, Sasso GJ, Uskokovic MR, Wang G, Reddy GS. Brown AJ, et al. Among authors: uskokovic mr. J Cell Biochem. 2005 Oct 15;96(3):569-78. doi: 10.1002/jcb.20553. J Cell Biochem. 2005. PMID: 16088954

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