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Whole genome association analysis shows that ACE is a risk factor for Alzheimer's disease and fails to replicate most candidates from Meta-analysis.
Int J Mol Epidemiol Genet. 2010;1(1):19-30. Epub 2009 Jul 26.
Int J Mol Epidemiol Genet. 2010.
PMID: 21537449
Free PMC article.
Genetic control of human brain transcript expression in Alzheimer disease.
Webster JA, Gibbs JR, Clarke J, Ray M, Zhang W, Holmans P, Rohrer K, Zhao A, Marlowe L, Kaleem M, McCorquodale DS 3rd, Cuello C, Leung D, Bryden L, Nath P, Zismann VL, Joshipura K, Huentelman MJ, Hu-Lince D, Coon KD, Craig DW, Pearson JV; NACC-Neuropathology Group; Heward CB, Reiman EM, Stephan D, Hardy J, Myers AJ.
Webster JA, et al.
Am J Hum Genet. 2009 Apr;84(4):445-58. doi: 10.1016/j.ajhg.2009.03.011.
Am J Hum Genet. 2009.
PMID: 19361613
Free PMC article.
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GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
Reiman EM, Webster JA, Myers AJ, Hardy J, Dunckley T, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Huentelman MJ, Craig DW, Coon KD, Liang WS, Herbert RH, Beach T, Rohrer KC, Zhao AS, Leung D, Bryden L, Marlowe L, Kaleem M, Mastroeni D, Grover A, Heward CB, Ravid R, Rogers J, Hutton ML, Melquist S, Petersen RC, Alexander GE, Caselli RJ, Kukull W, Papassotiropoulos A, Stephan DA.
Reiman EM, et al. Among authors: rohrer kc.
Neuron. 2007 Jun 7;54(5):713-20. doi: 10.1016/j.neuron.2007.05.022.
Neuron. 2007.
PMID: 17553421
Free PMC article.
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A survey of genetic human cortical gene expression.
Myers AJ, Gibbs JR, Webster JA, Rohrer K, Zhao A, Marlowe L, Kaleem M, Leung D, Bryden L, Nath P, Zismann VL, Joshipura K, Huentelman MJ, Hu-Lince D, Coon KD, Craig DW, Pearson JV, Holmans P, Heward CB, Reiman EM, Stephan D, Hardy J.
Myers AJ, et al.
Nat Genet. 2007 Dec;39(12):1494-9. doi: 10.1038/ng.2007.16. Epub 2007 Nov 4.
Nat Genet. 2007.
PMID: 17982457
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The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts.
Myers AJ, Pittman AM, Zhao AS, Rohrer K, Kaleem M, Marlowe L, Lees A, Leung D, McKeith IG, Perry RH, Morris CM, Trojanowski JQ, Clark C, Karlawish J, Arnold S, Forman MS, Van Deerlin V, de Silva R, Hardy J.
Myers AJ, et al.
Neurobiol Dis. 2007 Mar;25(3):561-70. doi: 10.1016/j.nbd.2006.10.018. Epub 2006 Dec 15.
Neurobiol Dis. 2007.
PMID: 17174556
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