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Naive CD8⁺ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics.
Neller MA, Ladell K, McLaren JE, Matthews KK, Gostick E, Pentier JM, Dolton G, Schauenburg AJ, Koning D, Fontaine Costa AI, Watkins TS, Venturi V, Smith C, Khanna R, Miners K, Clement M, Wooldridge L, Cole DK, van Baarle D, Sewell AK, Burrows SR, Price DA, Miles JJ. Neller MA, et al. Among authors: dolton g. Immunol Cell Biol. 2015 Aug;93(7):625-33. doi: 10.1038/icb.2015.17. Epub 2015 Mar 24. Immunol Cell Biol. 2015. PMID: 25801351 Free PMC article.
Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors.
Szomolay B, Liu J, Brown PE, Miles JJ, Clement M, Llewellyn-Lacey S, Dolton G, Ekeruche-Makinde J, Lissina A, Schauenburg AJ, Sewell AK, Burrows SR, Roederer M, Price DA, Wooldridge L, van den Berg HA. Szomolay B, et al. Among authors: dolton g. Immunol Cell Biol. 2016 Jul;94(6):573-82. doi: 10.1038/icb.2016.12. Epub 2016 Feb 5. Immunol Cell Biol. 2016. PMID: 26846725 Free PMC article.
Polypropylene Sulfide Nanoparticle p24 Vaccine Promotes Dendritic Cell-Mediated Specific Immune Responses against HIV-1.
Caucheteux SM, Mitchell JP, Ivory MO, Hirosue S, Hakobyan S, Dolton G, Ladell K, Miners K, Price DA, Kan-Mitchell J, Sewell AK, Nestle F, Moris A, Karoo RO, Birchall JC, Swartz MA, Hubbel JA, Blanchet FP, Piguet V. Caucheteux SM, et al. Among authors: dolton g. J Invest Dermatol. 2016 Jun;136(6):1172-1181. doi: 10.1016/j.jid.2016.01.033. Epub 2016 Feb 16. J Invest Dermatol. 2016. PMID: 26896775 Free article.
Purity of transferred CD8(+) T cells is crucial for safety and efficacy of combinatorial tumor immunotherapy in the absence of SHP-1.
Watson HA, Dolton G, Ohme J, Ladell K, Vigar M, Wehenkel S, Hindley J, Mohammed RN, Miners K, Luckwell RA, Price DA, Matthews RJ, Ager A. Watson HA, et al. Among authors: dolton g. Immunol Cell Biol. 2016 Sep;94(8):802-8. doi: 10.1038/icb.2016.45. Epub 2016 Jul 19. Immunol Cell Biol. 2016. PMID: 27430370 Free PMC article.
PD-1+ Polyfunctional T Cells Dominate the Periphery after Tumor-Infiltrating Lymphocyte Therapy for Cancer.
Donia M, Kjeldsen JW, Andersen R, Westergaard MCW, Bianchi V, Legut M, Attaf M, Szomolay B, Ott S, Dolton G, Lyngaa R, Hadrup SR, Sewell AK, Svane IM. Donia M, et al. Among authors: dolton g. Clin Cancer Res. 2017 Oct 1;23(19):5779-5788. doi: 10.1158/1078-0432.CCR-16-1692. Epub 2017 Jul 5. Clin Cancer Res. 2017. PMID: 28679768 Free PMC article. Clinical Trial.
ADAM17-dependent proteolysis of L-selectin promotes early clonal expansion of cytotoxic T cells.
Mohammed RN, Wehenkel SC, Galkina EV, Yates EK, Preece G, Newman A, Watson HA, Ohme J, Bridgeman JS, Durairaj RRP, Moon OR, Ladell K, Miners KL, Dolton G, Troeberg L, Kashiwagi M, Murphy G, Nagase H, Price DA, Matthews RJ, Knäuper V, Ager A. Mohammed RN, et al. Among authors: dolton g. Sci Rep. 2019 Apr 2;9(1):5487. doi: 10.1038/s41598-019-41811-z. Sci Rep. 2019. PMID: 30940840 Free PMC article.
Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Dolton G, Rius C, Wall A, Szomolay B, Bianchi V, Galloway SAE, Hasan MS, Morin T, Caillaud ME, Thomas HL, Theaker S, Tan LR, Fuller A, Topley K, Legut M, Attaf M, Hopkins JR, Behiry E, Zabkiewicz J, Alvares C, Lloyd A, Rogers A, Henley P, Fegan C, Ottmann O, Man S, Crowther MD, Donia M, Svane IM, Cole DK, Brown PE, Rizkallah P, Sewell AK. Dolton G, et al. Cell. 2023 Aug 3;186(16):3333-3349.e27. doi: 10.1016/j.cell.2023.06.020. Epub 2023 Jul 24. Cell. 2023. PMID: 37490916 Free article.
57 results