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Transient receptor potential ankyrin 1 receptor activation in vitro and in vivo by pro-tussive agents: GRC 17536 as a promising anti-tussive therapeutic.
Mukhopadhyay I, Kulkarni A, Aranake S, Karnik P, Shetty M, Thorat S, Ghosh I, Wale D, Bhosale V, Khairatkar-Joshi N. Mukhopadhyay I, et al. Among authors: khairatkar joshi n. PLoS One. 2014 May 12;9(5):e97005. doi: 10.1371/journal.pone.0097005. eCollection 2014. PLoS One. 2014. PMID: 24819048 Free PMC article.
Blocking TRPA1 in Respiratory Disorders: Does It Hold a Promise?
Mukhopadhyay I, Kulkarni A, Khairatkar-Joshi N. Mukhopadhyay I, et al. Among authors: khairatkar joshi n. Pharmaceuticals (Basel). 2016 Nov 5;9(4):70. doi: 10.3390/ph9040070. Pharmaceuticals (Basel). 2016. PMID: 27827953 Free PMC article. Review.
Discovery of 2-((2-chloro-6-fluorophenyl)amino)-N-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-7,8-dihydro-1H-[1,4]dioxino[2',3':3,4]benzo[1,2-d]imidazole-5-carboxamide as potent, selective and efficacious microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor.
Muthukaman N, Deshmukh S, Sarode N, Tondlekar S, Tambe M, Pisal D, Shaikh M, Kattige VG, Honnegowda S, Karande V, Kulkarni A, Jadhav SB, Mahat MYA, Gudi GS, Khairatkar-Joshi N, Gharat LA. Muthukaman N, et al. Among authors: khairatkar joshi n. Bioorg Med Chem Lett. 2016 Dec 15;26(24):5977-5984. doi: 10.1016/j.bmcl.2016.10.079. Epub 2016 Nov 1. Bioorg Med Chem Lett. 2016. PMID: 27865703
Design, synthesis and pharmacological evaluation of novel polycyclic heteroarene ethers as PDE10A inhibitors: part II.
Das S, Shelke DE, Harde RL, Avhad VB, Khairatkar-Joshi N, Gullapalli S, Gupta PK, Gandhi MN, Bhateja DK, Bajpai M, Joshi AA, Marathe MY, Gudi GS, Jadhav SB, Mahat MY, Thomas A. Das S, et al. Among authors: khairatkar joshi n. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3238-42. doi: 10.1016/j.bmcl.2014.06.028. Epub 2014 Jun 19. Bioorg Med Chem Lett. 2014. PMID: 24980052
Tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors: SAR and in vivo efficacy in hyperalgesia pain model.
Muthukaman N, Tambe M, Shaikh M, Pisal D, Deshmukh S, Tondlekar S, Sarode N, Narayana L, Gajera JM, Kattige VG, Honnegowda S, Karande V, Kulkarni A, Behera D, Jadhav SB, Gudi GS, Khairatkar-Joshi N, Gharat LA. Muthukaman N, et al. Among authors: khairatkar joshi n. Bioorg Med Chem Lett. 2017 Jun 1;27(11):2594-2601. doi: 10.1016/j.bmcl.2017.03.068. Epub 2017 Mar 24. Bioorg Med Chem Lett. 2017. PMID: 28400234
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