Krynetskaia NF - Search Results

1

Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells.

Diouf B, Cheng Q, Krynetskaia NF, Yang W, Cheok M, Pei D, Fan Y, Cheng C, Krynetskiy EY, Geng H, Chen S, Thierfelder WE, Mullighan CG, Downing JR, Hsieh P, Pui CH, Relling MV, Evans WE. Diouf B, et al. Among authors: krynetskaia nf. Nat Med. 2011 Sep 25;17(10):1298-303. doi: 10.1038/nm.2430. Nat Med. 2011. PMID: 21946537 Free PMC article.

2

Msh2 deficiency attenuates but does not abolish thiopurine hematopoietic toxicity in msh2-/- mice.

Krynetskaia NF, Brenner TL, Krynetski EY, Du W, Panetta JC, Ching-Hon P, Evans WE. Krynetskaia NF, et al. Mol Pharmacol. 2003 Aug;64(2):456-65. doi: 10.1124/mol.64.2.456. Mol Pharmacol. 2003. PMID: 12869651

3

A novel protein complex distinct from mismatch repair binds thioguanylated DNA.

Krynetski EY, Krynetskaia NF, Gallo AE, Murti KG, Evans WE. Krynetski EY, et al. Among authors: krynetskaia nf. Mol Pharmacol. 2001 Feb;59(2):367-74. doi: 10.1124/mol.59.2.367. Mol Pharmacol. 2001. PMID: 11160874

4

A nuclear protein complex containing high mobility group proteins B1 and B2, heat shock cognate protein 70, ERp60, and glyceraldehyde-3-phosphate dehydrogenase is involved in the cytotoxic response to DNA modified by incorporation of anticancer nucleoside analogues.

Krynetski EY, Krynetskaia NF, Bianchi ME, Evans WE. Krynetski EY, et al. Among authors: krynetskaia nf. Cancer Res. 2003 Jan 1;63(1):100-6. Cancer Res. 2003. PMID: 12517784

5

Human RNase H-mediated RNA cleavage from DNA-RNA duplexes is inhibited by 6-deoxythioguanosine incorporation into DNA.

Krynetskaia NF, Krynetski EY, Evans WE. Krynetskaia NF, et al. Mol Pharmacol. 1999 Oct;56(4):841-8. Mol Pharmacol. 1999. PMID: 10496969

6

Thioguanine substitution alters DNA cleavage mediated by topoisomerase II.

Krynetskaia NF, Cai X, Nitiss JL, Krynetski EY, Relling MV. Krynetskaia NF, et al. FASEB J. 2000 Nov;14(14):2339-44. doi: 10.1096/fj.00-0089com. FASEB J. 2000. PMID: 11053256

7

Structure and dynamics of thioguanine-modified duplex DNA.

Somerville L, Krynetski EY, Krynetskaia NF, Beger RD, Zhang W, Marhefka CA, Evans WE, Kriwacki RW. Somerville L, et al. Among authors: krynetskaia nf. J Biol Chem. 2003 Jan 10;278(2):1005-11. doi: 10.1074/jbc.M204243200. Epub 2002 Oct 24. J Biol Chem. 2003. PMID: 12401802 Free article.

8

Methylation of mercaptopurine, thioguanine, and their nucleotide metabolites by heterologously expressed human thiopurine S-methyltransferase.

Krynetski EY, Krynetskaia NF, Yanishevski Y, Evans WE. Krynetski EY, et al. Among authors: krynetskaia nf. Mol Pharmacol. 1995 Jun;47(6):1141-7. Mol Pharmacol. 1995. PMID: 7603453

9

Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians.

Tai HL, Krynetski EY, Yates CR, Loennechen T, Fessing MY, Krynetskaia NF, Evans WE. Tai HL, et al. Among authors: krynetskaia nf. Am J Hum Genet. 1996 Apr;58(4):694-702. Am J Hum Genet. 1996. PMID: 8644731 Free PMC article.

10

Deoxythioguanosine triphosphate impairs HIV replication: a new mechanism for an old drug.

Krynetskaia NF, Feng JY, Krynetski EY, Garcia JV, Panetta JC, Anderson KS, Evans WE. Krynetskaia NF, et al. FASEB J. 2001 Sep;15(11):1902-8. doi: 10.1096/fj.01-0124com. FASEB J. 2001. PMID: 11532970

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