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A common 5'-UTR variant in MATE2-K is associated with poor response to metformin.
Choi JH, Yee SW, Ramirez AH, Morrissey KM, Jang GH, Joski PJ, Mefford JA, Hesselson SE, Schlessinger A, Jenkins G, Castro RA, Johns SJ, Stryke D, Sali A, Ferrin TE, Witte JS, Kwok PY, Roden DM, Wilke RA, McCarty CA, Davis RL, Giacomini KM. Choi JH, et al. Among authors: stryke d. Clin Pharmacol Ther. 2011 Nov;90(5):674-84. doi: 10.1038/clpt.2011.165. Epub 2011 Sep 28. Clin Pharmacol Ther. 2011. PMID: 21956618 Free PMC article.
Functional characterization of liver enhancers that regulate drug-associated transporters.
Kim MJ, Skewes-Cox P, Fukushima H, Hesselson S, Yee SW, Ramsey LB, Nguyen L, Eshragh JL, Castro RA, Wen CC, Stryke D, Johns SJ, Ferrin TE, Kwok PY, Relling MV, Giacomini KM, Kroetz DL, Ahituv N. Kim MJ, et al. Among authors: stryke d. Clin Pharmacol Ther. 2011 Apr;89(4):571-8. doi: 10.1038/clpt.2010.353. Epub 2011 Mar 2. Clin Pharmacol Ther. 2011. PMID: 21368754 Free PMC article.
Identification and characterization of proximal promoter polymorphisms in the human concentrative nucleoside transporter 2 (SLC28A2).
Yee SW, Shima JE, Hesselson S, Nguyen L, De Val S, Lafond RJ, Kawamoto M, Johns SJ, Stryke D, Kwok PY, Ferrin TE, Black BL, Gurwitz D, Ahituv N, Giacomini KM. Yee SW, et al. Among authors: stryke d. J Pharmacol Exp Ther. 2009 Mar;328(3):699-707. doi: 10.1124/jpet.108.147207. Epub 2008 Dec 19. J Pharmacol Exp Ther. 2009. PMID: 19098160 Free PMC article.
Identification and characterization of novel polymorphisms in the basal promoter of the human transporter, MATE1.
Ha Choi J, Wah Yee S, Kim MJ, Nguyen L, Ho Lee J, Kang JO, Hesselson S, Castro RA, Stryke D, Johns SJ, Kwok PY, Ferrin TE, Goo Lee M, Black BL, Ahituv N, Giacomini KM. Ha Choi J, et al. Among authors: stryke d. Pharmacogenet Genomics. 2009 Oct;19(10):770-80. doi: 10.1097/FPC.0b013e328330eeca. Pharmacogenet Genomics. 2009. PMID: 19745787 Free PMC article.
Genetic and epigenetic regulation of the organic cation transporter 3, SLC22A3.
Chen L, Hong C, Chen EC, Yee SW, Xu L, Almof EU, Wen C, Fujii K, Johns SJ, Stryke D, Ferrin TE, Simko J, Chen X, Costello JF, Giacomini KM. Chen L, et al. Among authors: stryke d. Pharmacogenomics J. 2013 Apr;13(2):110-20. doi: 10.1038/tpj.2011.60. Epub 2012 Jan 10. Pharmacogenomics J. 2013. PMID: 22231567 Free PMC article.
47 results