Lawson JA - Search Results

1

Potent renin inhibitory peptides containing hydrophilic end groups.

Bundy GL, Pals DT, Lawson JA, Couch SJ, Lipton MF, Mauragis MA. Bundy GL, et al. Among authors: lawson ja. J Med Chem. 1990 Aug;33(8):2276-83. doi: 10.1021/jm00170a036. J Med Chem. 1990. PMID: 2197413

2

Renin inhibitory peptides. Incorporation of polar, hydrophilic end groups into an active renin inhibitory peptide template and their evaluation in a human renin infused rat model and in conscious sodium-depleted monkeys.

Thaisrivongs S, Pals DT, DuCharme DW, Turner SR, DeGraaf GL, Lawson JA, Couch SJ, Williams MV. Thaisrivongs S, et al. Among authors: lawson ja. J Med Chem. 1991 Feb;34(2):633-42. doi: 10.1021/jm00106a026. J Med Chem. 1991. PMID: 1995887

3

Rat model for evaluating inhibitors of human renin.

Pals DT, Lawson JA, Couch SJ. Pals DT, et al. Among authors: lawson ja. J Pharmacol Methods. 1990 Jul;23(4):239-45. doi: 10.1016/0160-5402(90)90052-m. J Pharmacol Methods. 1990. PMID: 2196401

4

Synthesis and renin inhibitory activity of angiotensinogen analogues having dehydrostatine, Leu psi [CH2S]Val, or Leu psi [CH2SO]Val at the P1-P1' cleavage site.

Smith CW, Saneii HH, Sawyer TK, Pals DT, Scahill TA, Kamdar BV, Lawson JA. Smith CW, et al. Among authors: lawson ja. J Med Chem. 1988 Jul;31(7):1377-82. doi: 10.1021/jm00402a022. J Med Chem. 1988. PMID: 3290486

5

alpha-Methylproline-containing renin inhibitory peptides: in vivo evaluation in an anesthetized, ganglion-blocked, hog renin infused rat model.

Thaisrivongs S, Pals DT, Lawson JA, Turner SR, Harris DW. Thaisrivongs S, et al. Among authors: lawson ja. J Med Chem. 1987 Mar;30(3):536-41. doi: 10.1021/jm00386a016. J Med Chem. 1987. PMID: 3546690

6

Appraisal of a glycopeptide cloaking strategy for a therapeutic oligopeptide: glycopeptide analogs of the renin inhibitor ditekiren.

Harrison AW, Fisher JF, Guido DM, Couch SJ, Lawson JA, Sutter DM, Williams MV, DeGraaf GL, Rogers JE, Pals DT, et al. Harrison AW, et al. Among authors: lawson ja. Bioorg Med Chem. 1994 Dec;2(12):1339-61. doi: 10.1016/s0968-0896(00)82086-6. Bioorg Med Chem. 1994. PMID: 7788297

7

Hormonal and cardiovascular effects of losartan (DuP753), an angiotensin receptor antagonist, in nonhuman primates.

DeGraaf GL, Pals DT, Couch SJ, Lawson JA. DeGraaf GL, et al. Among authors: lawson ja. J Pharmacol Exp Ther. 1993 Jan;264(1):6-10. J Pharmacol Exp Ther. 1993. PMID: 8423551

8

An orally active inhibitor of renin.

Pals DT, Thaisrivongs S, Lawson JA, Kati WM, Turner SR, DeGraaf GL, Harris DW, Johnson GA. Pals DT, et al. Among authors: lawson ja. Hypertension. 1986 Dec;8(12):1105-12. doi: 10.1161/01.hyp.8.12.1105. Hypertension. 1986. PMID: 3539793

9

Cardiovascular effects of a renin inhibitor in relation to posture in nonhuman primates.

Pals DT, DeGraaf GL, Kati WM, Lawson JA, Smith CW, Skala GF. Pals DT, et al. Among authors: lawson ja. Clin Exp Hypertens A. 1985;7(1):105-21. doi: 10.3109/10641968509074757. Clin Exp Hypertens A. 1985. PMID: 2986882

10

Significant depletion of NPY in the innervation of the rat mesenteric, renal arteries and kidneys in experimentally (aorta coarctation) induced hypertension.

Ballesta J, Lawson JA, Pals DT, Ludens JH, Lee YC, Bloom SR, Polak JM. Ballesta J, et al. Among authors: lawson ja. Histochemistry. 1987;87(3):273-8. doi: 10.1007/BF00492421. Histochemistry. 1987. PMID: 3654276

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