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PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network.
Ying H, Elpek KG, Vinjamoori A, Zimmerman SM, Chu GC, Yan H, Fletcher-Sananikone E, Zhang H, Liu Y, Wang W, Ren X, Zheng H, Kimmelman AC, Paik JH, Lim C, Perry SR, Jiang S, Malinn B, Protopopov A, Colla S, Xiao Y, Hezel AF, Bardeesy N, Turley SJ, Wang YA, Chin L, Thayer SP, DePinho RA. Ying H, et al. Among authors: lim c. Cancer Discov. 2011 Jul;1(2):158-69. doi: 10.1158/2159-8290.CD-11-0031. Epub 2011 May 23. Cancer Discov. 2011. PMID: 21984975 Free PMC article.
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik JH, Lim C, Guimaraes AR, Martin ES, Chang J, Hezel AF, Perry SR, Hu J, Gan B, Xiao Y, Asara JM, Weissleder R, Wang YA, Chin L, Cantley LC, DePinho RA. Ying H, et al. Among authors: lim c. Cell. 2012 Apr 27;149(3):656-70. doi: 10.1016/j.cell.2012.01.058. Cell. 2012. PMID: 22541435 Free PMC article.
Mig-6 controls EGFR trafficking and suppresses gliomagenesis.
Ying H, Zheng H, Scott K, Wiedemeyer R, Yan H, Lim C, Huang J, Dhakal S, Ivanova E, Xiao Y, Zhang H, Hu J, Stommel JM, Lee MA, Chen AJ, Paik JH, Segatto O, Brennan C, Elferink LA, Wang YA, Chin L, DePinho RA. Ying H, et al. Among authors: lim c. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6912-7. doi: 10.1073/pnas.0914930107. Epub 2010 Mar 29. Proc Natl Acad Sci U S A. 2010. PMID: 20351267 Free PMC article.
FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis.
Gan B, Lim C, Chu G, Hua S, Ding Z, Collins M, Hu J, Jiang S, Fletcher-Sananikone E, Zhuang L, Chang M, Zheng H, Wang YA, Kwiatkowski DJ, Kaelin WG Jr, Signoretti S, DePinho RA. Gan B, et al. Among authors: lim c. Cancer Cell. 2010 Nov 16;18(5):472-84. doi: 10.1016/j.ccr.2010.10.019. Cancer Cell. 2010. PMID: 21075312 Free PMC article.
Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer.
Kapoor A, Yao W, Ying H, Hua S, Liewen A, Wang Q, Zhong Y, Wu CJ, Sadanandam A, Hu B, Chang Q, Chu GC, Al-Khalil R, Jiang S, Xia H, Fletcher-Sananikone E, Lim C, Horwitz GI, Viale A, Pettazzoni P, Sanchez N, Wang H, Protopopov A, Zhang J, Heffernan T, Johnson RL, Chin L, Wang YA, Draetta G, DePinho RA. Kapoor A, et al. Among authors: lim c. Cell. 2014 Jul 3;158(1):185-197. doi: 10.1016/j.cell.2014.06.003. Epub 2014 Jun 19. Cell. 2014. PMID: 24954535 Free PMC article.
Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer.
Kapoor A, Yao W, Ying H, Hua S, Liewen A, Wang Q, Zhong Y, Wu CJ, Sadanandam A, Hu B, Chang Q, Chu GC, Al-Khalil R, Jiang S, Xia H, Fletcher-Sananikone E, Lim C, Horwitz GI, Viale A, Pettazzoni P, Sanchez N, Wang H, Protopopov A, Zhang J, Heffernan T, Johnson RL, Chin L, Wang YA, Draetta G, DePinho RA. Kapoor A, et al. Among authors: lim c. Cell. 2019 Nov 14;179(5):1239. doi: 10.1016/j.cell.2019.10.037. Cell. 2019. PMID: 31730860 Free PMC article. No abstract available.
Final results of RIGHT Choice: Ribociclib plus endocrine therapy vs combination chemotherapy in premenopausal women with clinically aggressive HR+/HER2- advanced breast cancer.
Lu YS, Bin Mohd Mahidin EI, Azim H, Eralp Y, Yap YS, Im SA, Rihani J, Gokmen E, El Bastawisy A, Karadurmus N, Lim YN, Lim CS, Duc LT, Chung WP, Babu KG, Penkov K, Bowles J, Alfaro TD, Wu J, Gao M, Slimane K, El Saghir NS. Lu YS, et al. Among authors: lim cs. J Clin Oncol. 2024 May 21:JCO2400144. doi: 10.1200/JCO.24.00144. Online ahead of print. J Clin Oncol. 2024. PMID: 38771995
Frequency and mortality rate following antimicrobial-resistant bloodstream infections in tertiary-care hospitals compared with secondary-care hospitals.
Lim C, Hantrakun V, Klaytong P, Rangsiwutisak C, Tangwangvivat R, Phiancharoen C, Doung-Ngern P, Kripattanapong S, Hinjoy S, Yingyong T, Rojanawiwat A, Unahalekhaka A, Kamjumphol W, Khobanan K, Leethongdee P, Lorchirachoonkul N, Khusuwan S, Siriboon S, Chamnan P, Vijitleela A, Fongthong T, Noiprapai K, Boonyarit P, Srisuphan V, Sartorius B, Stelling J, Turner P, Day NPJ, Limmathurotsakul D. Lim C, et al. PLoS One. 2024 May 20;19(5):e0303132. doi: 10.1371/journal.pone.0303132. eCollection 2024. PLoS One. 2024. PMID: 38768224 Free PMC article.
7,754 results