Kirschning A - Search Results

1

The interplay between mutasynthesis and semisynthesis: generation and evaluation of an ansamitocin library.

Eichner S, Knobloch T, Floss HG, Fohrer J, Harmrolfs K, Hermane J, Schulz A, Sasse F, Spiteller P, Taft F, Kirschning A. Eichner S, et al. Among authors: kirschning a. Angew Chem Int Ed Engl. 2012 Jan 16;51(3):752-7. doi: 10.1002/anie.201106249. Epub 2011 Dec 1. Angew Chem Int Ed Engl. 2012. PMID: 22135226 No abstract available.

2

Synthesis of 4-amino 3,4-dideoxy-D-arabino-heptulosonic acid 7-phosphate, the biosynthetic precursor of C7N units in ansamycin antibiotics.

Kirschning A, Bergon P, Wang JJ, Breazeale S, Floss HG. Kirschning A, et al. Carbohydr Res. 1994 Apr 1;256(2):245-56. doi: 10.1016/0008-6215(94)84211-6. Carbohydr Res. 1994. PMID: 8187101 No abstract available.

3

Functionalized Polymers-Emerging Versatile Tools for Solution-Phase Chemistry and Automated Parallel Synthesis.

Kirschning A, Monenschein H, Wittenberg R. Kirschning A, et al. Angew Chem Int Ed Engl. 2001 Feb 16;40(4):650-679. Angew Chem Int Ed Engl. 2001. PMID: 11241594

4

PASSflow Syntheses Using Functionalized Monolithic Polymer/Glass Composites in Flow-Through Microreactors Part of these studies were supported by the Fonds der Chemischen Industrie and the European Community (EC project number HPRI-CT-1999-00085) for which we are grateful. PASSflow=Polymer Assisted Solution-Phase Synthesis technique in flow-through mode.

Kirschning A, Altwicker C, Dräger G, Harders J, Hoffmann N, Hoffmann U, Schönfeld H, Solodenko W, Kunz U. Kirschning A, et al. Angew Chem Int Ed Engl. 2001 Nov 5;40(21):3995-3998. Angew Chem Int Ed Engl. 2001. PMID: 12404472 No abstract available.

5

Solid-phase-assisted solution-phase synthesis with minimum purification-preparation of 2-deoxyglycoconjugates from thioglycosides.

Jaunzems J, Hofer E, Jesberger M, Sourkouni-Argirusi G, Kirschning A. Jaunzems J, et al. Among authors: kirschning a. Angew Chem Int Ed Engl. 2003 Mar 10;42(10):1166-70. doi: 10.1002/anie.200390307. Angew Chem Int Ed Engl. 2003. PMID: 12640651 No abstract available.

6

Determination of the cryptic stereochemistry of the first PKS chain-extension step in ansamitocin biosynthesis by Actinosynnema pretiosum.

Kubota T, Brünjes M, Frenzel T, Xu J, Kirschning A, Floss HG. Kubota T, et al. Among authors: kirschning a. Chembiochem. 2006 Aug;7(8):1221-5. doi: 10.1002/cbic.200500506. Chembiochem. 2006. PMID: 16927319

7

Chemoenzymatic approaches toward dechloroansamitocin P-3.

Meyer A, Brünjes M, Taft F, Frenzel T, Sasse F, Kirschning A. Meyer A, et al. Among authors: kirschning a. Org Lett. 2007 Apr 12;9(8):1489-92. doi: 10.1021/ol0702270. Epub 2007 Mar 23. Org Lett. 2007. PMID: 17378571

8

Total synthesis approaches to natural product derivatives based on the combination of chemical synthesis and metabolic engineering.

Kirschning A, Taft F, Knobloch T. Kirschning A, et al. Org Biomol Chem. 2007 Oct 21;5(20):3245-59. doi: 10.1039/b709549j. Epub 2007 Sep 10. Org Biomol Chem. 2007. PMID: 17912378 Review.

9

Stereochemical determination of thuggacins A-C, highly active antibiotics from the myxobacterium Sorangium cellulosum.

Bock M, Buntin K, Müller R, Kirschning A. Bock M, et al. Among authors: kirschning a. Angew Chem Int Ed Engl. 2008;47(12):2308-11. doi: 10.1002/anie.200704897. Angew Chem Int Ed Engl. 2008. PMID: 18275054 No abstract available.

10

Highly active ansamitocin derivatives: mutasynthesis using an AHBA-blocked mutant.

Taft F, Brünjes M, Floss HG, Czempinski N, Grond S, Sasse F, Kirschning A. Taft F, et al. Among authors: kirschning a. Chembiochem. 2008 May 5;9(7):1057-60. doi: 10.1002/cbic.200700742. Chembiochem. 2008. PMID: 18381586 No abstract available.

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