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Identification of new aminoacid amides containing the imidazo[2,1-b]benzothiazol-2-ylphenyl moiety as inhibitors of tumorigenesis by oncogenic Met signaling.
Furlan A, Colombo F, Kover A, Issaly N, Tintori C, Angeli L, Leroux V, Letard S, Amat M, Asses Y, Maigret B, Dubreuil P, Botta M, Dono R, Bosch J, Piccolo O, Passarella D, Maina F. Furlan A, et al. Among authors: angeli l. Eur J Med Chem. 2012 Jan;47(1):239-54. doi: 10.1016/j.ejmech.2011.10.051. Epub 2011 Nov 4. Eur J Med Chem. 2012. PMID: 22138308
Dihydro-alkylthio-benzyl-oxopyrimidines as inhibitors of reverse transcriptase: synthesis and rationalization of the biological data on both wild-type enzyme and relevant clinical mutants.
Mugnaini C, Alongi M, Togninelli A, Gevariya H, Brizzi A, Manetti F, Bernardini C, Angeli L, Tafi A, Bellucci L, Corelli F, Massa S, Maga G, Samuele A, Facchini M, Clotet-Codina I, Armand-Ugón M, Esté JA, Botta M. Mugnaini C, et al. Among authors: angeli l. J Med Chem. 2007 Dec 27;50(26):6580-95. doi: 10.1021/jm0708230. Epub 2007 Dec 6. J Med Chem. 2007. PMID: 18052319
Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (S-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants.
Radi M, Maga G, Alongi M, Angeli L, Samuele A, Zanoli S, Bellucci L, Tafi A, Casaluce G, Giorgi G, Armand-Ugon M, Gonzalez E, Esté JA, Baltzinger M, Bec G, Dumas P, Ennifar E, Botta M. Radi M, et al. Among authors: angeli l. J Med Chem. 2009 Feb 12;52(3):840-51. doi: 10.1021/jm801330n. J Med Chem. 2009. PMID: 19140683
64 results