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[(18)F]FLT-PET imaging does not always "light up" proliferating tumor cells.
Zhang CC, Yan Z, Li W, Kuszpit K, Painter CL, Zhang Q, Lappin PB, Nichols T, Lira ME, Affolter T, Fahey NR, Cullinane C, Spilker M, Zasadny K, O'Brien P, Buckman D, Wong A, Christensen JG. Zhang CC, et al. Clin Cancer Res. 2012 Mar 1;18(5):1303-12. doi: 10.1158/1078-0432.CCR-11-1433. Epub 2011 Dec 14. Clin Cancer Res. 2012. PMID: 22170262
Monitoring cellular accumulation of 3'-deoxy-3'-fluorothymidine (FLT) and its monophosphate metabolite (FLT-MP) by LC-MS/MS as a measure of cell proliferation in vitro.
Li W, Araya M, Elliott M, Kang X, Gerk PM, Halquist MS, Karnes HT, Zhang C, O'Brien PJ. Li W, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Oct 15;879(28):2963-70. doi: 10.1016/j.jchromb.2011.08.024. Epub 2011 Aug 31. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21925976
Comprehensive bioimaging with fluorinated nanoparticles using breathable liquids.
Kurczy ME, Zhu ZJ, Ivanisevic J, Schuyler AM, Lalwani K, Santidrian AF, David JM, Giddabasappa A, Roberts AJ, Olivos HJ, O'Brien PJ, Franco L, Fields MW, Paris LP, Friedlander M, Johnson CH, Epstein AA, Gendelman HE, Wood MR, Felding BH, Patti GJ, Spilker ME, Siuzdak G. Kurczy ME, et al. Nat Commun. 2015 Jan 20;6:5998. doi: 10.1038/ncomms6998. Nat Commun. 2015. PMID: 25601659 Free PMC article.
Liquid chromatography-tandem mass spectrometry method for quantification of thymidine kinase activity in human serum by monitoring the conversion of 3'-deoxy-3'-fluorothymidine to 3'-deoxy-3'-fluorothymidine monophosphate.
Faria M, Halquist MS, Kindt E, Li W, Karnes HT, O'Brien PJ. Faria M, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Oct 15;907:13-20. doi: 10.1016/j.jchromb.2012.08.024. Epub 2012 Aug 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 22995377
Luciferase does not Alter Metabolism in Cancer Cells.
Johnson CH, Fisher TS, Hoang LT, Felding BH, Siuzdak G, O'Brien PJ. Johnson CH, et al. Metabolomics. 2014 Jun 1;10(3):354-360. doi: 10.1007/s11306-014-0622-5. Metabolomics. 2014. PMID: 24791164 Free PMC article.
Trajectory of Recovery following ORIF for Distal Radius Fractures.
Larose G, Roffey DM, Broekhuyse HM, Guy P, O'Brien P, Lefaivre KA. Larose G, et al. Among authors: o brien p. J Wrist Surg. 2023 Jul 13;13(3):230-235. doi: 10.1055/s-0043-1771045. eCollection 2024 Jun. J Wrist Surg. 2023. PMID: 38808181
2,878 results